Senior Research Scientist, Method Development (LC-MS)

220 Altasciences Company Inc; Laval (administrative region); On-site; CAD 120,000 - 160,000; Full time

Benefits offered by this job

Health/Dental/Vision plans

401(k)/RRSP with Employer Match

Paid vacation and holidays

Paid sick and bereavement leave

Employee Assistance & Telehealth

Job summary

Altasciences seeks a Senior Research Scientist with proven LC-MS/MS bioanalytical expertise to lead method development for regulatory-ready analyses across multiple modalities. You will design experiments, optimize workflows, and ensure data quality for project success.

Responsibilities include developing robust LC-MS/MS methods, overseeing sample prep and data interpretation, and collaborating with validation and operations for seamless method transfer.

Qualifications

• Typically 5–8+ years of LC-MS/MS bioanalysis experience.
• Experience leading bioanalytical method development projects.
• Ability to interpret data and communicate complex concepts clearly.

Responsibilities

• Develop and optimize robust bioanalytical methods using LC-MS/MS in regulatory-compliant settings.
• Oversee sample prep, analysis, and data interpretation against timelines.
• Troubleshoot bioanalytical challenges through systematic design and root-cause analysis.
• Lead client discussions and scientific meetings on methods and results.
• Prepare, review, and approve method development reports and SOPs.
• Collaborate with validation and operations for method transfer.
• Stay current with LC-MS technologies and implement improvements.
• Adhere to Health and Safety protocols and lab upkeep.

Skills

LC-MS/MS bioanalysis

Scientific writing

Project leadership

Analytical chemistry

Education

Master's or Ph.D. in Biochemistry, Chemistry, Analytical Chemistry, or related

Bachelor's degree with significant relevant experience

Tools

LC-MS/MS instrumentation

Job description

About The Role

We are seeking a highly motivated and experienced Senior Research Scientist with strong expertise in bioanalytical mass spectrometry to join our Method Development team. The successful candidate will lead the development and optimization of regulatory-ready bioanalytical methods using liquid chromatography-mass spectrometry (LC-MS/MS) for a variety of therapeutic modalities, including small molecules, peptides, biologics, biomarkers, and oligonucleotides.

What You'll Do

• Develop and optimize robust bioanalytical methods using LC-MS/MS in compliance with regulatory standards.
• Perform and oversee sample preparation, analysis, and data interpretation while meeting project timelines and quality expectations.
• Investigate and resolve complex bioanalytical challenges through systematic troubleshooting, experimental design, and root-cause assessment.
• Participate in client discussions and scientific meetings, communicating method development strategies, analytical results, and technical recommendations.
• Prepare, review, and approve method development reports, SOPs, and other technical documentation as required.
• Collaborate with validation and operational teams to support successful method transfer and implementation.
• Stay current with advancements in LC-MS technologies and best practices to support continuous improvement.
• Adhere to Health and Safety protocols, including personal protective practices and laboratory upkeep.

What You'll Need to Succeed

• Master's or Ph.D. in Biochemistry, Chemistry, Analytical Chemistry, or a related discipline;
• a Bachelor's degree with significant relevant experience may also be considered.
• Typically 5-8+ years of relevant experience in LC-MS/MS bioanalysis, with demonstrated experience independently leading bioanalytical method development projects.
• Experience in sample preparation techniques appropriate to the analyte type (e.g., protein precipitation, solid-phase extraction, immunoaffinity-based approaches, enzymatic digestion).
• Strong scientific writing, communication, and presentation skills, with the ability to effectively communicate complex technical concepts to both scientific and non-scientific stakeholders.

Altasciences strives to provide a French work environment for its employees in Quebec. Altasciences has taken all reasonable measures to avoid imposing the above language requirement. This requirement is essential for the position of Senior Research Scientist, Method development (LCMS) in particular, but without limitation, for the following reason(s): The requirement to have study protocols read and documented in English as required by industry regulatory agencies.

What We Offer

Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.

• Health/Dental/Vision Insurance Plans
• 401(k)/RRSP with Employer Match
• Paid Vacation and Holidays
• Paid Sick and Bereavement Leave
• Employee Assistance & Telehealth Program

Altasciences' Incentive Programs Include:

• Training & Development Programs
• Employee Referral Bonus Program
• Annual Performance Reviews

At Altasciences we all move in unison to assist and work in the discovery, development, and manufacturing of new drug therapies to get them faster to people who need them. No matter your role, we all play an important part and you will have a significant impact on the health and well-being of people across the globe. By living our values of Employee Development, Customer Focus, Quality and Excellence, Respect and Integrity, we look to foster a passionate and collaborative work environment and we are looking for talented and enthusiastic people, like you, to join our growing team!

Whether you're a recent college graduate or seeking your next career opportunity, it's time to discover your future at Altasciences.

We are better together and together We Are Altasciences.

Altasciences is an equal opportunity employer committed to diversity and inclusion.

Our goal is to attract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives.

All qualified applicants will receive consideration for employment without regard to age, race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability or any other protected grounds under applicable legislation.

Reasonable accommodations for persons with disabilities during the recruitment process are available upon request.

Join us at Altasciences!