Postdoctoral Fellow

University of Alberta; Edmonton; On-site; CAD 50,000 - 70,000; Full time

Job summary

The University of Alberta seeks a Postdoctoral Fellow in Medical Microbiology and Immunology for research in structure-based drug design using cryo-EM. This role involves express and purifying proteins, conducting experiments, and mentoring students. A Ph.D. in a relevant field is mandatory. Located in Edmonton, the position is full-time with potential for renewal.

Qualifications

• Ph.D. degree required.
• Strong hands-on experience in protein engineering essential.
• Knowledge in structural biology helpful but training provided.

Responsibilities

• Expression and purification of protein complexes.
• Conducting various biophysical and structural biology experiments.
• Writing manuscripts and grant applications.

Skills

Protein engineering

Biophysical characterization

Teamwork

Communication skills

Education

Ph.D. in structural biology, molecular biology, chemical biology, biochemistry, or related field

Job description

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Postdoctoral Fellow

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Department Faculty of Medicine & Dentistry - Medical Microbiology and Immunology Dept

Posted date May 13, 2025

Closing date June 24, 2025

Position Type Full Time - Trust Funded

Description

This position is part of the Post Doctoral Fellows Association and has an initial appointment of 1 year with the possibility of renewal.

Location - This role is in-person at North Campus Edmonton.

Working at the University of Alberta

The University of Alberta acknowledges that we are located on Treaty 6 territory, and respects the histories, languages and cultures of First Nations, Métis, Inuit and all FirstPeoples of Canada, whose presence continues to enrich our vibrant community.

The University of Alberta is a community of knowledge seekers, change makers and world shapers who lead with purpose each and every day. We are home to over 14,000 faculty and staff, more than 40,000 students and a growing community of 300,000 alumni worldwide.

Your work will have a meaningful influence on a fascinating cross-section of people — from our students and community members, to our renowned researchers and innovators, making discoveries and generating solutions that make the world healthier, safer, stronger and more just. Learn more.

Working for the Department of Medical Microbiology and Immunology

The Department of Medical Microbiology and Immunology is a research-intensive unit that pursues dynamic projects in the areas of immunology, virology, and bacteriology. Our research foci include host-pathogen interactions, virus infection and replication, immune responses to pathogens, bacterial pathogenesis, as well as autoimmunity and cancer immunology. Our research goals are to create and improve therapeutic agents, vaccines, and physiological interventions to improve health, and diminish or prevent disease.

Position Summary

The structural biology laboratory of Kalyan Das at MMI, University of Alberta, Canada invites applications from highly motivated researchers interested in pursuing a career in structure-based drug design using single-particle cryo-EM. A candidate should have a Ph. D. degree in structural biology, molecular biology, chemical biology, biochemistry, or a related field with a proven track record. Strong hands-on experience in protein engineering, protein expression in bacteria and insect cells, and biophysical characterization of proteins and macromolecule assemblies is essential. Knowledge in structural biology is helpful; however, successful candidates will have the training opportunities to carry out structural studies by single-particle cryo-EM. A qualified person should be a team player and should have strong writing and verbal communication skills.

Our structural biology laboratory is equipped or access to state-of-the-art Krios G4 TEM, Vitrobot Mark IV and Leica GP2, multiple advanced GPU workstations for cryo-EM. The lab is also equipped with Akta Pure 25 integrated with Wyatt Optilab T-rEX, miniDAWN TREOS, and DynoPro NanoStar for purification and characterization of macromolecules

Duties

• Expression and purification of protein complexes
• Design and characterization of macromolecular assemblies
• Conducting various biophysical and structural biology experiments and analyses.
• Designing experiments, and maintaining lab instruments
• Training PhD, masters, and undergraduate researchers
• Writing manuscripts and grant applications
  
  

Qualifications

Ph. D. degree in structural biology, molecular biology, chemical biology, biochemistry, or a related field.

Application Instructions

Click "Apply" to submit the following application documents:

• Cover letter
• Curriculum vitae
• List of publications
  
  

At the University of Alberta, we are committed to creating an inclusive and accessible hiring process for all candidates. If you require accommodations to participate in the interview process, please let us know at the time of booking your interview and we will make every effort to accommodate your needs.

We thank all applicants for their interest; however, only those individuals selected for an interview will be contacted.

All University employees have a responsibility to foster a workplace that prioritizes safety in all its forms—physical, cultural, and psychological. This is achieved by promoting a safe environment, adhering to all safety laws, policies and procedures, completing all required safety training, identifying hazards and implementing controls, reporting incidents, and contributing to a culture of inclusivity and respect, while endeavoring to ensure that all colleagues feel valued and safe to express their thoughts, perspectives and concerns.

The University of Alberta is committed to creating a university community where everyone feels valued, barriers to success are removed, and thriving connections are fostered. We welcome applications from all qualified persons. We encourage women, First Nations, Métis and Inuit persons, members of visible minority groups, persons with disabilities, persons of any sexual orientation or gender identity and expression, and all those who may contribute to the further diversification of ideas and the University to apply.

L’Université de l’Alberta s’engage à créer une communauté universitaire où chaque personne se sent valorisée, où les obstacles à la réussite sont éliminés et où des connexions enrichissantes peuvent se développer. Nous accueillons les demandes de toutes les personnes qualifiées. Nous encourageons les femmes; Premières nations, Métis et Inuits; membres des groupes minoritaires visibles; personnes handicapées; personnes ayant une orientation sexuelle ou une identité et une expression sexospécifique; et tous ceux qui peuvent contribuer à la diversification des idées et à l'université à postuler.

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Note: This opportunity will be available until midnight June 24, 2025, Edmonton, Alberta local time.

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