Biotherapeutics Research Scientist II

zymeworks-careers; Vancouver; On-site; CAD 85,000 - 120,000; Full time

Benefits offered by this job

Industry leading vacation

Medical, dental and vision benefits by

Zymelife health and wellness benefits

Matching RRSP / Pension program

Employee Share Purchase Program

Employee Equity Program

Paid time off to volunteer

Job summary

Zymeworks is seeking a hands-on protein scientist for a full-time onsite role in Vancouver, BC. You will purify proteins and characterize multispecific antibody-based therapeutics, contributing to a fast-paced development program.

The role requires 2–3 years of related experience or a Master’s degree, with strong expertise in purification, analytical methods, and developability assays. You will collaborate across teams and maintain rigorous lab practices to drive project success.

Qualifications

• A BSc in a relevant scientific discipline and 2–3 years of related experience, or a Master’s degree with equivalent education/experience.
• Hands-on experience in protein purification (affinity, protein A/G/L, IEX, SEC).
• Experience in protein analytical techniques (PAGE, CE-SDS, ELISA, MSD, UPLC-SEC).
• Knowledge of therapeutics developability assays (AC-SINS, non-specific ELISA, HIC).
• Understanding of different affinity measurement methods (SPR, BLI, KinExA, on-cell binding).
• Ability to work collaboratively in a cross-functional team.
• Good organizational skills and ability to work in a fast-paced environment.
• Ability to present data at team and inter-departmental meetings.

Responsibilities

• Perform protein purification and analytical characterization of various protein-based molecules.
• Design, plan and execute experiments to characterize multispecific antibody-based therapeutics through developability assays.
• May assist in affinity measurements to screen protein therapeutics.
• Troubleshoot methods, suggest improvements and develop new technologies for project advancement.
• Write standard operating procedures for methods requiring significant technical understanding, data manipulation and calculations.
• Analyze data, draw conclusions and participate in cross-departmental activities.
• Maintain a clean, organized and operational lab.
• Conduct all activities in accordance with scientific standards, OH&S regulations and established policies and practices.
• Actively work to foster an environment of effective and collaborative working relationships across the organization.

Skills

Protein purification

Protein analytics

Developability assays

Affinity measurements

Cross-functional collaboration

Organization

Data presentation

Education

BSc in Biochemistry or related field

Master’s degree in related field

Job description

Zymeworks is seeking a hands-on protein scientist for a full-time onsite role in Vancouver, BC. You will purify proteins and characterize multispecific antibody-based therapeutics, contributing to a fast-paced development program.

The role requires 2–3 years of related experience or a Master’s degree, with strong expertise in purification, analytical methods, and developability assays. You will collaborate across teams and maintain rigorous lab practices to drive project success.