Research Scientist I - Pharmacokinetics

AbCellera Biologics Inc.; Vancouver; On-site; CAD 80,000 - 98,000; Full time

Benefits offered by this job

Equity

Annual bonus

RRSP contribution

Active Lifestyle Allowance

Comprehensive health benefits

Job summary

AbCellera Biologics Inc. in Vancouver seeks a Research Scientist with hands-on antibody PK experience to bridge discovery and the clinic. You will execute bioanalytical and PK activities, focusing on T-cell engager programs, and collaborate with In Vivo PK, Non-Clinical Safety, Modeling, Protein Science, and Discovery Biology teams.

You will drive ELISA, MSD and other assays, develop innovative analytical methods, and communicate data across teams to progress programs toward clinic.

Qualifications

• PhD in a related field or MSc+3–5 years in academia or industry.
• BSc+5+ years in a relevant setting also acceptable.
• Hands-on antibody PK and LBA experience (ELISA, MSD) required.
• Strong documentation and communication skills.

Responsibilities

• Generate bioanalytical and PK data from samples for antibody programs.
• Collaborate with cross‑functional PK and discovery teams.
• Define PK strategies to progress projects to the clinic, esp. TCEs.
• Perform ELISA, MSD and other assays with accuracy.
• Develop and implement innovative bioanalytical methods.
• Analyze, interpret and communicate data with teammates.

Skills

antibody pharmacokinetics

ELISA

MSD

non-compartmental PK data analysis

Education

PhD in related field

MSc + 3-5 yrs experience

BSc + 5+ yrs experience

Tools

WinNonlin

Job description

Each of us cares about someone who will need medicines. That's why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.

We are looking for a Research Scientist with hands-on experience with antibody therapeutics to join our multidisciplinary Pharmacokinetics (PK) team. Based in Vancouver, you will be instrumental in bridging the gap between discovery and the clinic, specifically executing bioanalytical and pharmacokinetic activities with a focus on T-cell engager (TCE) programs. In this role, you will collaborate with cross-functional teams, including In Vivo Pharmacology, Non-Clinical Safety, Modeling and Simulations, Protein Science, and Discovery Biology, to support the progression of our projects from discovery to development.

How you might spend your days

• Generating bioanalytical and PK data from biological samples to critically assess therapeutic antibody programs
• Collaborating with cross-functional project teams as a representative of the PK function
• Defining the PK strategy to progress projects to the clinic, with a focus on T-cell engagers
• Performing ELISA, MSD, and other bioanalytical assays on study samples with a high degree of efficiency and accuracy
• Driving the development and implementation of innovative bioanalytical methods to support our PK research and development pipeline
• Collaborating with teammates to solve problems, analyze, interpret, and communicate data

We'd love to hear from you if

• You have a strong understanding of antibody pharmacokinetics
• You have hands-on experience with ligand binding assays (LBA) such as ELISA, MSD, or other plate based assays
• You have a PhD in a related field; or an MSc plus 3-5 years of experience in an academic or industry environment; or a BSc plus 5+ years of related experience
• You excel in documentation and organizational skills and clearly communicate scientific and technical concepts - both verbally and in writing
• You have experience with non-compartmental PK data analysis (WinNonlin), considered a strong asset

What we offer

AbCellera's hiring range for this role is CAD $80,000 - $98,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you'll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.

About AbCellera

Creating medicines is the most important work we can do.

We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women's health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline.

Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug (IND)-enabling activities, and more than 20 active discovery programs across multiple modalities and indications.

We believe that when tenacious people share a vision and work together, they can truly have a positive impact. That's why we hire for character and intelligence, not just for CVs or experience.

We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.