Postdoc Oral Lipid Based Formulations

Johnson & Johnson; Beerse; Sur place; EUR 60 000 - 96 000; Plein temps

Résumé du poste

Johnson & Johnson Beerse invites applications for a Postdoctoral Scholar (Postdoc) to work in a collaborative setting on advanced in vitro characterization methods that connect lipid formulation behavior to drug delivery potential, aiming to design next-generation lipid-based strategies for beyond rule of five candidates.

The two-year assignment will include in vitro and in vivo translation activities, reporting through scientific forums, and manuscript preparation while aligning with IP

Qualifications

• PhD in a relevant science or engineering field with independence in designing experiments.
• Experience linking lipid formulation behavior to drug delivery potential.
• Strong English communication and scientific output record.
• Willingness to work on-site in Beerse, Belgium.

Responsabilités

• Build and explore an advanced in vitro characterization toolbox for lipid formulations.
• Develop high-throughput workflows to screen lipolysis and dissolution- permeation.
• Design lipid formulation strategies for oral delivery of bRo5 molecules.
• Contribute to in vivo translation with PK studies and mechanistic experiments.
• Present findings and support manuscript preparation consistent with IP guidance.

Connaissances

English communication

Scientific independence

Biopharmaceutics knowledge

Publications/patents track record

Beerse on-site willingness

Formation

PhD (or near completion) in Pharmaceutical Sciences, Chemical Engineering, Chemistry, Bioengineering, or related field

Outils

COSMO

lipolysis models

dissolution-permeation methods

PAMPA variants

phase characterization during digestion/dissolution

Description du poste

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Career Programs

Job Sub Function

Post Doc – R&D Product Development

Job Category

Career Program

All Job Posting Locations

Beerse, Antwerp, Belgium

Job Description

The role

We are seeking a talented Postdoctoral Scholar (Postdoc) to work in a highly collaborative environment for a two‑year assignment during which you will explore advanced in vitro characterization methods that connect lipid formulation behavior to drug delivery potential ultimately aiming to design next‑generation lipid based formulation strategies for beyond rule of five (bRo5) drug candidates.

Key Responsibilities

• Build and explore an advanced in vitro characterization toolbox e.g. coupling dissolution, lipolysis, precipitation/crystallization, mucus penetration, and permeation readouts for lipid‑based formulations.
• Explore downscaling/high‑throughput feasibility for e.g. lipolysis and dissolution‑permeation workflows to enable efficient screening and optimization.
• Design and optimize next‑level lipid formulation strategies for the oral delivery of bRo5 molecules
• Support in vivo translation e.g. contributing to rat PK/lymphatic transport studies and mechanistic experiments
• Communicate scientific outcomes through internal presentations and scientific forums and contribute to manuscript preparation and publication strategy consistent with IP guidance.

Required Qualifications

• PhD (or near completion) in Pharmaceutical Sciences, Chemical Engineering, Chemistry, Bioengineering, or a closely related discipline.
• Demonstrated ability to design and execute experimental research with scientific independence (literature review, planning, lab execution, data analysis, reporting).
• Experience relevant to the project focus: lipid‑based formulations and/or biopharmaceutics tools that link formulation behavior (dispersion/dissolution/digestion/precipitation) to delivery potential (permeation).
• Strong written and verbal communication skills in English and a track record of scientific output (publications/presentations and/or patents).
• Willingness to work on‑site in Beerse, Belgium with hands‑on lab activities.

Preferred Qualifications

• Experience with one or more of: lipolysis/digestion models, dissolution‑permeation methods, membrane permeability models (e.g., PAMPA variants), mucus assays, precipitation/crystallization analytics, or phase characterization during digestion/dissolution.
• Familiarity with lipid-based formulation optimization strategies and/or exploration of in‑silico tools to guide formulation design (e.g., COSMO).
• Exposure to translational modeling and/or in vivo study support (PBPK/PK; oral absorption/lymphatic transport).

#DPDS

Required Skills

Preferred Skills:

The Anticipated Base Pay Range For This Position Is

€60,000.00 - €96,255.00

Benefits

In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans. For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.

• This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.