MES (PAS-X) Technical Lead and Modeller | Life Sciences

Capgemini Engineering; Diegem; Hybrid; EUR 85,000 - 135,000; Full time

Job summary

Capgemini Engineering is seeking a senior MES Technical Lead and Modeller to drive a PAS-X MES rollout across multiple manufacturing sites for a global pharmaceutical client. You will lead architectural decisions, oversee MES configuration, and coordinate with vendors, IT/OT teams, and deployment leads to ensure a compliant, scalable solution.

The role requires strong leadership, 6–8 years in MES/MOM with PAS-X, and experience in regulated environments with validation frameworks like GAMP 5 and

Qualifications

• 6–8 years of MES/MOM implementation in industrial manufacturing with hands-on PAS-X experience.
• Strong grounding in enterprise and OT architectures, system integration, and ISA‑95 knowledge.
• Experience in regulated industries (Pharmaceuticals/Life Sciences) with validation methods including GAMP 5 and CSV.
• Proven stakeholder engagement across IT, OT, Manufacturing and Quality teams; capable of bridging technical and business outcomes.
• Leadership and problem solving with a continuous improvement mindset; able to make decisions under pressure.

Responsibilities

• Lead architectural and technical decisions for PAS-X MES rollout across multi-site deployments.
• Oversee end‑to‑end MES configuration: workflows, MBRs, ESP, and integration with ERP, SCADA, LIMS, Historian.
• Ensure OT/IT interface design meets functional and non‑functional requirements; support master data alignment.
• Coordinate across vendors, system integrators, automation providers, and infrastructure teams; support Program Managers.
• Lead testing lifecycle: SIT, UAT, defect management; support Validation/CSV activities in regulated environments.
• Manage deployment, go-live, and stabilisation activities; troubleshoot complex site‑level issues.
• Drive knowledge transfer and governance; promote reusable, standardised solutions.

Skills

MES/MOM

PAS-X

OT/IT integrations

ISA-95

Enterprise architecture

Validation & CSV

Stakeholder management

Leadership

English

French/Dutch

Job description

At Capgemini Engineering, the world leader in engineering services, we bring together a global team of engineers, scientists, and architects to help the worlds mostinnovative companies unleash their potential. From autonomous cars to life-saving robots, our digital and software technology experts think outside the box as theyprovide unique R&D and engineering services across all industries. Join us for a career full of opportunities. Where you can make a difference. Where no two days arethe same.

Job Description

We are looking for a MES Technical Lead and Modeller to join a large-scale PAS-X MES roll-out program, supporting a global pharmaceutical client across multiple manufacturing sites. This is a senior technical role requiring both deep hands-on expertise and the leadership capability to guide vendors, stakeholders, and local teams through complex, multi-site implementations. In this role you will play a key role in:

• Leading architectural and technical decision-making for the PAS-X MES roll-out, ensuring alignment between the global core model and local site implementations, minimising unnecessary customisations and maintaining consistency across the program.
• Overseeing end-to-end MES configuration activities, including workflows, forms, Master Batch Records (MBRs), general MBRs (gMBRs), and Electronic Signatures & Permissions (ESP), while governing integration with enterprise and shop-floor systems such as ERP, SCADA, LIMS, and Historian.
• Ensuring the proper design and implementation of OT/IT interfaces and integration patterns, validating technical solutions against both functional and non-functional requirements, and supporting master data management and alignment processes across sites.
• Providing technical coordination across vendors and third-party suppliers, including system integrators, automation providers, and infrastructure teams, while supporting Program Managers and Deployment Leads on all technical and solution-related matters.
• Leading technical activities across the full testing lifecycle, including System Integration Testing (SIT), User Acceptance Testing (UAT), and defect management, as well as supporting Validation and Qualification activities in regulated environments.
• Overseeing deployment, go-live, and technical stabilisation activities, contributing to the resolution of complex issues and troubleshooting efforts to ensure a smooth transition at each site.
• Driving knowledge management and governance, including technical knowledge transfer to local teams, continuous improvement of documentation and implementation guidelines, and promoting solution reusability and standardisation across manufacturing sites.

Your profile

• 6-8 years of proven experience in MES/MOM implementation within industrial manufacturing environments, with hands-on expertise in the PAS-X platform, including MES/MOM solutions and OT/IT integrations.
• Strong technical grounding in enterprise and OT application architectures, system integration and interface design, and solid knowledge of the ISA-95 standard, with demonstrated experience across multi-site deployment programs.
• Experience in regulated industries such as Pharmaceuticals or Life Sciences is highly valued, along with familiarity with validation methodologies and compliance frameworks including GAMP 5 and Computer System Validation (CSV).
• A track record of effective stakeholder engagement, with the ability to communicate clearly and confidently across IT, OT, Manufacturing, and Quality teams - bridging the gap between technical detail and business outcomes.
• Strong leadership and problem-solving capabilities, including a continuous improvement mindset, analytical thinking, and the confidence to make technical decisions under pressure in complex, fast-moving program environments.
• Fluency in English is required next to French or Dutch.
• Mobility to the client's location in Beerse with some homeworking possible.

What You'll Love About Working Here

• Engineering Horizons - A global conference crafted exclusively for Capgemini Engineering colleagues, where excellence takes centre stage. Immerse yourself in opportunities to showcase your talents and connect with the brightest minds in engineering across the planet.
• FlexAbroad - Employees in 20+ countries can work abroad for up to 45 days in a 12-month period, giving you the flexibility to blend work and exploration across the globe.
• Digital Campuses and Academy - Our engineering academy offers more than 60,000 hours of training, as well as our digital campus on GenAI, data, and sustainability, supporting digital learning in the flow of work from awareness to expert certifications.
• Global Tech Challenges - Capgemini hosts annual group-wide competitions, such as the Global Data Science Challenge and Tech4PositiveFutures. These aim to address world issues like climate change and biodiversity by applying technology for innovative solutions. The Future of X is a Global Ideation Campaign that looks for ideas for iconic anchor R&I projects and demonstrators of technology. Winning ideas were funded up to 100K€.

Capgemini is a global business and technology transformation partner, helping organizations to accelerate their dual transition to a digital and sustainable world, while creating tangible impact for enterprises and society. It is a responsible and diverse group of 340,000 team members in more than 50 countries. With its strong over 55-year heritage, Capgemini is trusted by its clients to unlock the value of technology to address the entire breadth of their business needs. It delivers end-to-end services and solutions leveraging strengths from strategy and design to engineering, all fueled by its market-leading capabilities in AI, generative AI, cloud and data, combined with its deep industry expertise and partner ecosystem.