Senior Synthetic Organic Chemist — Drug Discovery & Scale-Up

Placements24; Bloemfontein; Hybride; ZAR 900 000 - 1 200 000; Plein temps

Avantages offerts par ce poste

Competitive salary

Medical, disability, and life保险

Retirement savings plan

Paid time off and holidays

Professional development and CONFERENC

Conference attendance

Modern labs and instrumentation

Collaborative research environment

Impactful pharmaceutical development

Résumé du poste

Placements24 in Bloemfontein, South Africa, seeks a Senior Synthetic Organic Chemist to lead design and execution of multi-step syntheses for potential therapeutics. You will optimize conditions, characterize products using NMR, MS, and HPLC, and troubleshoot challenging problems in collaboration with medicinal and analytical chemists.

The role emphasizes independence and teamwork within a state-of-the-art R&D laboratory, contributing to drug discovery programs and professional growth.

Qualifications

• PhD in Synthetic Organic Chemistry or closely related field.
• 5+ years of post-doctoral or industry experience in synthetic organic chemistry.
• Expertise in modern synthetic methodologies including asymmetric synthesis and organometallic chemistry.
• Hands-on experience with a wide range of synthetic reactions and purification techniques.
• Proficiency in NMR, MS, and chromatography for structural elucidation.
• Experience developing scalable synthetic routes is desirable.
• Strong problem-solving, organizational, and time management skills.
• Excellent written and verbal communication for collaboration and reporting.
• Ability to work independently and in a team in Bloemfontein.

Responsabilités

• Design and execute complex multi-step synthetic routes to novel organic molecules.
• Optimize reaction conditions to improve yield, purity, and scalability.
• Characterize synthesized compounds using modern analytical techniques (NMR, MS, HPLC).
• Troubleshoot challenging synthetic problems and develop innovative solutions.
• Collaborate with medicinal chemists to generate analogues for SAR studies.
• Work with process chemists to develop scalable and robust synthetic routes.
• Maintain detailed laboratory notebooks and research reports.
• Stay current with advancements in synthetic organic chemistry literature.
• Ensure adherence to laboratory safety regulations and procedures.

Connaissances

Multi-step synthesis

Asymmetric synthesis

Organometallic chemistry

Problem solving

Formation

Ph.D. in Synthetic Organic Chemistry

Outils

NMR spectroscopy

Mass spectrometry

Chromatography

Description du poste

Placements24 in Bloemfontein, South Africa, seeks a Senior Synthetic Organic Chemist to lead design and execution of multi-step syntheses for potential therapeutics. You will optimize conditions, characterize products using NMR, MS, and HPLC, and troubleshoot challenging problems in collaboration with medicinal and analytical chemists.

The role emphasizes independence and teamwork within a state-of-the-art R&D laboratory, contributing to drug discovery programs and professional growth.