Senior Pharmaceutical Quality Control Analyst

Placements24; Centurion; On-site; ZAR 600,000 - 900,000; Full time

Benefits offered by this job

Medical aid

Provident fund

Performance-based bonuses

Professional development opportunities

Annual performance reviews

Job summary

Placements24 is seeking a Senior Pharmaceutical Quality Control Analyst for its Centurion facility in Gauteng. The role focuses on leading QC testing, method development, and ensuring GMP/GLP compliance to uphold product quality.

You will mentor junior staff, oversee analytical procedures (HPLC/GC/Karl Fischer), review data, and support audits and batch release decisions in a modern laboratory environment.

Qualifications

• 5–7 years of experience in a pharmaceutical QC lab.
• Proficient with pharmacopeias (USP/EP/BP) and regulatory guidelines.
• Experience troubleshooting analytical methods and equipment failures.
• Strong GMP/GLP knowledge and data integrity skills.
• Excellent documentation and cross-department collaboration.

Responsibilities

• Perform diverse analytical tests on raw materials, in-process samples and finished products (HPLC, GC, UV-Vis).
• Develop, validate and implement analytical methods per pharmacopeial standards.
• Interpret results, investigate OOS results, and document findings.
• Maintain GLP/GMP-compliant records and manage data integrity.
• Calibrate, maintain and troubleshoot lab equipment.
• Review data and support batch release decisions; contribute to audits.
• Mentor junior analysts and support continuous QC improvements.
• Lead in trainings on analytical techniques and regulatory compliance.
• Collaborate across departments to ensure product quality.

Skills

HPLC

GC

Karl Fischer

Dissolution testing

GMP/GLP

Documentation

Leadership

Education

Bachelor's or Master's in Chemistry/Analytical Chemistry/Pharmaceutical Sciences

Tools

HPLC systems

Gas Chromatography

Karl Fischer titrator

Dissolution apparatus

Job description

About the Role

Our client, a respected name in the pharmaceutical industry, is seeking a diligent and experienced Senior Pharmaceutical Quality Control Analyst to join their vital operations in Centurion, Gauteng . This role is crucial for ensuring the consistent quality and safety of pharmaceutical products through rigorous testing and analysis. The Senior QC Analyst will be responsible for overseeing a range of analytical procedures, ensuring adherence to strict regulatory standards and internal quality protocols. This position requires a meticulous approach, a deep understanding of analytical chemistry, and a commitment to maintaining the highest quality benchmarks. The ideal candidate will possess strong leadership qualities and the ability to guide and mentor junior analysts. Working within our state-of-the-art laboratory facilities, you will play a key role in upholding our client's reputation for excellence and compliance. We are looking for a dedicated professional who is passionate about quality assurance in the pharmaceutical sector.

Key Responsibilities

• Perform a wide variety of analytical tests on raw materials, in-process samples, and finished products using various laboratory techniques (e.g., HPLC, GC, UV-Vis, FTIR).
• Develop, validate, and implement analytical methods according to pharmacopeial standards and regulatory guidelines.
• Interpret test results, identify deviations, and investigate out-of-specification (OOS) results, documenting findings thoroughly.
• Maintain accurate and detailed laboratory records, ensuring compliance with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP).
• Calibrate, maintain, and troubleshoot laboratory equipment to ensure optimal performance and accuracy.
• Review and approve analytical data generated by junior analysts and contribute to batch release decisions.
• Participate in internal and external audits, providing necessary documentation and explanations.
• Contribute to the continuous improvement of quality control processes and procedures.
• Train and mentor junior Quality Control Analysts, providing guidance on analytical techniques and regulatory compliance.

Requirements

• Bachelor's or Master's degree in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related discipline.
• A minimum of 5-7 years of relevant experience in a pharmaceutical Quality Control laboratory environment.
• Extensive hands-on experience with analytical instrumentation such as HPLC, GC, Karl Fischer titrator, and dissolution apparatus.
• In-depth knowledge of pharmacopeias (e.g., USP, EP, BP) and regulatory guidelines (e.g., FDA, EMA, SAHPRA).
• Proven ability to troubleshoot analytical methods and equipment failures.
• Strong understanding of GMP/GLP principles and their application in a QC setting.
• Excellent documentation, record-keeping, and data integrity skills.
• Effective communication and interpersonal skills, with the ability to collaborate across departments.
• Leadership potential and experience in mentoring junior staff are highly desirable.

Benefits

• Our client offers a competitive salary commensurate with experience, along with a comprehensive benefits package including medical aid, a provident fund, and performance-based bonuses.
• Employees are provided with opportunities for continuous professional development, including advanced training courses and conference attendance.
• This role is based in our modern facility in Centurion, Gauteng , offering a stable and supportive work environment.
• We believe in investing in our employees' growth and well-being, providing a rewarding career path within a highly respected organization.
• Additional benefits include annual performance reviews and a supportive management team.