Senior Pharma Process Engineer - Scale-Up & GMP (Benoni)

Placements24; Benoni; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Medical aid

Retirement fund

Career progression opportunities

Job summary

Placements24 in Benoni, Gauteng, seeks a Senior Pharmaceutical Process Engineer for a state-of-the-art facility. You will design, implement, and optimize manufacturing processes, scale-up operations, and lead GMP-compliant projects.

You will oversee process validation, CAPAs, and safety, mentor junior engineers, and collaborate with R&D, QA, and manufacturing teams to drive continuous improvement and regulatory compliance.

Qualifications

• 6-8 years of progressive experience in process engineering within pharmaceutical/biotech industry.
• In-depth knowledge of pharmaceutical manufacturing equipment (reactors, dryers, filtration, tablet presses).
• Strong understanding of GMP, validation principles, and regulatory requirements.
• Experience in process scale-up, optimization and troubleshooting.
• Excellent analytical, problem-solving and project management skills.
• Strong technical writing and communication abilities.
• Ability to lead and mentor junior engineers.

Responsibilities

• Design, develop, optimize, and scale-up pharmaceutical manufacturing processes (batch, continuous, sterile).
• Lead process validation activities (IQ, OQ, PQ, cleaning validation).
• Troubleshoot deviations and implement CAPAs for quality and reliability.
• Conduct process hazard analyses and implement safety measures.
• Develop and maintain process documentation (P&IDs, SOPs, batch records).
• Collaborate with R&D, QA, Manufacturing Ops, and Maintenance.
• Stay abreast of new manufacturing technologies and best practices.
• Manage capital projects for equipment upgrades and new installations.
• Ensure GMP and regulatory compliance across activities.

Skills

Process engineering

GMP knowledge

Project management

Data analysis

Technical writing

Mentoring

Education

BEng/BSc in Chemical Engineering

Tools

Aspen Plus

Job description

Placements24 in Benoni, Gauteng, seeks a Senior Pharmaceutical Process Engineer for a state-of-the-art facility. You will design, implement, and optimize manufacturing processes, scale-up operations, and lead GMP-compliant projects.

You will oversee process validation, CAPAs, and safety, mentor junior engineers, and collaborate with R&D, QA, and manufacturing teams to drive continuous improvement and regulatory compliance.