Senior Pharmaceutical Process Engineer - Benoni

Placements24; Benoni; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Medical aid

Retirement fund

Career progression opportunities

Job summary

Placements24 in Benoni, Gauteng, seeks a Senior Pharmaceutical Process Engineer for a state-of-the-art facility. You will design, implement, and optimize manufacturing processes, scale-up operations, and lead GMP-compliant projects.

You will oversee process validation, CAPAs, and safety, mentor junior engineers, and collaborate with R&D, QA, and manufacturing teams to drive continuous improvement and regulatory compliance.

Qualifications

• 6-8 years of progressive experience in process engineering within pharmaceutical/biotech industry.
• In-depth knowledge of pharmaceutical manufacturing equipment (reactors, dryers, filtration, tablet presses).
• Strong understanding of GMP, validation principles, and regulatory requirements.
• Experience in process scale-up, optimization and troubleshooting.
• Excellent analytical, problem-solving and project management skills.
• Strong technical writing and communication abilities.
• Ability to lead and mentor junior engineers.

Responsibilities

• Design, develop, optimize, and scale-up pharmaceutical manufacturing processes (batch, continuous, sterile).
• Lead process validation activities (IQ, OQ, PQ, cleaning validation).
• Troubleshoot deviations and implement CAPAs for quality and reliability.
• Conduct process hazard analyses and implement safety measures.
• Develop and maintain process documentation (P&IDs, SOPs, batch records).
• Collaborate with R&D, QA, Manufacturing Ops, and Maintenance.
• Stay abreast of new manufacturing technologies and best practices.
• Manage capital projects for equipment upgrades and new installations.
• Ensure GMP and regulatory compliance across activities.

Skills

Process engineering

GMP knowledge

Project management

Data analysis

Technical writing

Mentoring

Education

BEng/BSc in Chemical Engineering

Tools

Aspen Plus

Job description

About the Role

Our client, a leading pharmaceutical manufacturer, is seeking an experienced Senior Pharmaceutical Process Engineer to join their state-of-the-art facility in Benoni, Gauteng . This role is critical for optimizing and scaling up pharmaceutical manufacturing processes to ensure efficiency, quality, and compliance. The Senior Process Engineer will be responsible for designing, implementing, and troubleshooting manufacturing processes, leading process improvement initiatives, and ensuring adherence to Good Manufacturing Practices (GMP). This is an outstanding opportunity for a skilled engineer to drive innovation and operational excellence in a challenging and rewarding pharmaceutical environment. The ideal candidate has a strong background in chemical or process engineering with specific experience in the pharmaceutical industry.

Key Responsibilities

• Design, develop, optimize, and scale-up pharmaceutical manufacturing processes, including batch processing, continuous manufacturing, and sterile operations.
• Lead process validation activities, including IQ, OQ, PQ, and cleaning validation.
• Troubleshoot process deviations and implement corrective and preventive actions (CAPAs) to ensure product quality and process reliability.
• Conduct process hazard analyses and implement safety measures to ensure a safe working environment.
• Develop and maintain process documentation, including P&IDs, SOPs, and batch records.
• Collaborate with cross-functional teams, including R&D, Quality Assurance, Manufacturing Operations, and Maintenance.
• Stay abreast of new manufacturing technologies and industry best practices to drive continuous improvement.
• Manage capital projects related to process equipment upgrades and new installations.
• Ensure all process engineering activities comply with GMP and regulatory requirements.

Requirements

• BEng or BSc in Chemical Engineering, Mechanical Engineering, or a related engineering discipline.
• A minimum of 6-8 years of progressive experience in process engineering within the pharmaceutical or biotechnology industry.
• In-depth knowledge of pharmaceutical manufacturing equipment (e.g., reactors, dryers, filtration systems, tablet presses).
• Strong understanding of GMP, validation principles, and regulatory requirements.
• Proven experience in process scale-up, optimization, and troubleshooting.
• Excellent analytical, problem-solving, and project management skills.
• Strong technical writing and communication abilities.
• Ability to lead and mentor junior engineers.
• Proficiency in process simulation software (e.g., Aspen Plus) is an advantage.
• Must be able to work on-site in Benoni, Gauteng .

Benefits

• Our client offers a competitive salary, excellent benefits package including medical aid and retirement fund, and significant opportunities for career progression.
• You will be part of an innovative pharmaceutical company committed to high-quality manufacturing standards.
• This role offers a chance to make a substantial impact on pharmaceutical production within the vibrant industrial hub of Benoni .