Senior Pharma Process Engineer - Scale-Up & cGMP

Placements24; Benoni; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Health coverage

Retirement contributions

Generous vacation time

Job summary

Placements24 is seeking a Senior Pharmaceutical Process Engineer for our Benoni, Gauteng operations. The role focuses on optimizing and troubleshooting manufacturing processes for pharmaceutical products in a cGMP environment.

You will lead process improvements, validation, and technology transfer efforts to ensure safe, compliant production of high-quality medicines. The ideal candidate holds a Master’s in Chemical Engineering with 7+ years in pharma/biotech process engineering, and

Qualifications

• Master's degree in Chemical Engineering, Mechanical Engineering, or a related field.
• Minimum 7 years of process engineering experience in pharma/biotech.
• Proven expertise in design, scale-up, validation, and optimization in a cGMP environment.
• Strong understanding of pharmaceutical manufacturing operations, equipment, and unit operations.
• Experience with process modeling software and DoE is a plus.
• Experience with quality risk management principles.
• Excellent problem-solving, analytical, and project management skills.
• Strong written and verbal communication; cross-functional collaboration.

Responsibilities

• Design, develop, and optimize manufacturing processes for pharmaceutical products, ensuring scalability and efficiency.
• Lead process validation activities, including protocol development, execution, and reporting.
• Troubleshoot manufacturing process deviations and implement CAPAs.
• Conduct PHAs and implement appropriate safety measures.
• Utilize engineering principles and statistical tools (Six Sigma, DoE) to improve process performance and product quality.
• Collaborate with R&D, Quality Assurance, and Production teams to support new product introductions and lifecycle management.
• Oversee technology transfer from laboratory to pilot plant and commercial manufacturing.
• Manage projects related to process upgrades, equipment installation, and facility modifications.
• Ensure compliance with cGMP, FDA, EMA, and other regulatory requirements.
• Develop and maintain SOPs and process documentation.
• Mentor junior engineers and provide technical guidance to manufacturing personnel.

Skills

Process design

Scale-up

Validation

CAPA

PHAs

Six Sigma

DoE

Project management

Cross-functional leadership

Communication

Education

Master's degree in Chemical Engineering

Tools

Process modeling software

Job description

Placements24 is seeking a Senior Pharmaceutical Process Engineer for our Benoni, Gauteng operations. The role focuses on optimizing and troubleshooting manufacturing processes for pharmaceutical products in a cGMP environment.

You will lead process improvements, validation, and technology transfer efforts to ensure safe, compliant production of high-quality medicines. The ideal candidate holds a Master’s in Chemical Engineering with 7+ years in pharma/biotech process engineering, and