Pharma Process Engineer: Scale-Up & cGMP Excellence

Placements24; Sandton; On-site; ZAR 900,000 - 1,500,000; Full time

Benefits offered by this job

Annual bonus

Medical and dental coverage

Provident fund

Professional development

Job summary

Placements24 is seeking a Chemical Process Engineer for an advanced pharmaceutical manufacturing facility in Sandton, Gauteng. The role focuses on designing and optimizing processes for pharmaceutical intermediates, scaling from lab to pilot and ensuring stringent cGMP compliance.

You will troubleshoot deviations, develop validation protocols, and collaborate with QA, Production and R&D to improve yield, cycle time and cost while maintaining high safety standards in a highly regulated

Qualifications

• Design, develop and optimize chemical processes for pharmaceutical intermediates.
• Scale-up of laboratory processes to pilot and commercial scales.
• Troubleshoot deviations and implement CAPAs.
• Maintain process documentation including batch records and validation protocols.
• Ensure manufacturing complies with cGMP, FDA, and other regs.
• Perform process hazard analyses and implement safety measures.
• Collaborate with QA, Production and R&D.
• Monitor performance and identify yield/cycle-time improvements.
• Assist in qualification and validation of new equipment and processes.

Responsibilities

• Design, develop and optimize chemical processes for pharmaceutical intermediates.
• Support scale-up from lab to pilot and production scales.
• Troubleshoot deviations and implement CAPAs.
• Maintain batch records, SOPs and validation protocols.
• Ensure compliance with cGMP and regulatory requirements.
• Conduct process hazard analyses and enforce safety measures.
• Collaborate cross-functionally with QA, Production and R&D.
• Monitor process performance for yield, cycle time and cost reductions.
• Assist in qualification/validation of new equipment and processes.

Skills

Chemical engineering

Scale-up expertise

Regulatory knowledge

Problem solving

Education

Bachelor's or Master's in Chemical Engineering

Tools

Process simulation (Aspen Plus)

Job description

Placements24 is seeking a Chemical Process Engineer for an advanced pharmaceutical manufacturing facility in Sandton, Gauteng. The role focuses on designing and optimizing processes for pharmaceutical intermediates, scaling from lab to pilot and ensuring stringent cGMP compliance.

You will troubleshoot deviations, develop validation protocols, and collaborate with QA, Production and R&D to improve yield, cycle time and cost while maintaining high safety standards in a highly regulated