Senior Computational Chemist – Drug Design & Lead Opt

Placements24; Benoni; Vor Ort; ZAR 900.000 - 1.300.000; Vollzeit

Benefits dieser Stelle

Health insurance

Retirement plan

Professional development opportunities

Bonuses and incentives

Zusammenfassung

Placements24 is seeking a Senior Computational Chemist to join its drug design team in Benoni, Gauteng. You will guide molecule design, optimize leads, and explore chemical space using QSAR and modern cheminformatics. Collaboration with chemists and biologists is essential to accelerate discovery.

The role emphasizes molecular modeling, QSAR, and software competencies, with mentorship of junior team members and contributions to reports and patents.

Qualifikationen

• Ph.D. in Computational Chemistry, Medicinal Chemistry, Cheminformatics, or related field.
• Minimum 5 years of relevant industry experience in computational chemistry applied to drug discovery.
• Proficiency in molecular modeling software and cheminformatics toolkits.
• Strong understanding of organic/medicinal chemistry and drug discovery processes.
• Experience with QSAR modeling, virtual screening, and lead optimization.
• Proficiency in Python for scripting and data analysis.
• Excellent analytical, problem-solving, and communication skills.

Aufgaben

• Utilize computational chemistry methods to support drug discovery programs.
• Design novel chemical entities with optimal pharmacokinetic and pharmacodynamic properties.
• Collaborate with medicinal chemists to interpret SAR and guide iterative design cycles.
• Develop and apply virtual screening strategies to identify hit compounds.
• Integrate cheminformatics tools and databases into drug design workflows.
• Analyze and interpret computational and experimental data to provide insights.
• Stay updated on advancements in computational chemistry and drug design.
• Contribute to research reports, publications, and patents.
• Mentor junior computational chemists and research associates in Benoni.

Kenntnisse

Python scripting

Data analysis

Analytical thinking

Communication

Ausbildung

PhD in Computational Chemistry

Tools

Schrödinger Suite

MOE

Sybyl

RDKit

Jobbeschreibung

Placements24 is seeking a Senior Computational Chemist to join its drug design team in Benoni, Gauteng. You will guide molecule design, optimize leads, and explore chemical space using QSAR and modern cheminformatics. Collaboration with chemists and biologists is essential to accelerate discovery.

The role emphasizes molecular modeling, QSAR, and software competencies, with mentorship of junior team members and contributions to reports and patents.