Lead Computational Chemist: Drug Discovery Leadership

Placements24; Kempton Park; Presencial; ZAR 1.200.000 - 2.000.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Performance bonus

Health insurance

Retirement plan

Professional development

Descripción de la vacante

Placements24 is seeking a Lead Computational Chemist in Gauteng to spearhead drug discovery efforts at a premier biopharmaceutical R&D site. You will guide a team of computational chemists and data scientists, applying cheminformatics, molecular modeling, docking, and QSAR to translate targets into drug candidates.

The role requires a Ph.D. and 7+ years in pharma computational chemistry, with leadership and collaboration across multidisciplinary teams.

Formación

• Ph.D. in Computational Chemistry, Cheminformatics, Theoretical Chemistry, or a related field.
• 7+ years of progressive experience in computational chemistry, with significant drug discovery experience in pharma.
• Expertise with molecular modeling software (Schrödinger, MOE, Discovery Studio) and visualization tools.
• Strong understanding of cheminformatics, databases, and data mining; programming for workflows (Python/Perl) preferred.
• Excellent leadership and communication skills with a track record of delivering projects.

Responsabilidades

• Lead and mentor a team of computational chemists and data scientists.
• Develop and implement computational strategies for hit identification and lead optimization.
• Use molecular modeling, docking, virtual screening, and QSAR to guide drug design.
• Integrate structural biology, assays, and ADMET into workflows.
• Collaborate with medicinal chemists to design synthesis targets and interpret results.
• Manage computational resources and large-scale simulations.
• Contribute to project strategy and present findings to stakeholders.
• Foster innovation and scientific excellence within the team.

Conocimientos

Leadership

Drug discovery experience

Science communication

Project management

Educación

Ph.D. in Computational Chemistry or related field

Herramientas

Schrödinger Suite

MOE

Discovery Studio

Python

Perl

Descripción del empleo

Placements24 is seeking a Lead Computational Chemist in Gauteng to spearhead drug discovery efforts at a premier biopharmaceutical R&D site. You will guide a team of computational chemists and data scientists, applying cheminformatics, molecular modeling, docking, and QSAR to translate targets into drug candidates.

The role requires a Ph.D. and 7+ years in pharma computational chemistry, with leadership and collaboration across multidisciplinary teams.