Senior Analytical Chemistry Specialist - On-Site Nelspruit

Placements24; Mbombela (Nelspruit); On-site; ZAR 500,000 - 800,000; Full time

Job summary

Placements24 is seeking a Senior Analytical Chemistry Specialist to join its quality control and research division in Nelspruit, Mpumalanga. You will develop, validate, and execute analytical methods to ensure the quality, purity, and stability of pharmaceutical products and raw materials.

You will work with HPLC, GC, UV-Vis, FTIR, KF titration, and regulatory-compliant method validation, mentor junior chemists, and contribute to process improvements in a GMP environment.

Qualifications

• MSc or PhD in Analytical Chemistry or related field.
• Minimum 5 years' experience in pharmaceutical analytical chemistry, GMP environment preferred.
• Extensive hands-on experience with chromatographic techniques (HPLC/UPLC/GC) and spectroscopic methods (UV-Vis/FTIR).
• Proficiency in method validation according to regulatory guidelines (ICH).
• Strong understanding of pharmaceutical product development and manufacturing processes.
• Experience with Karl Fischer titration/dissolution testing and other pharmacopeial methods.
• Excellent data analysis and interpretation skills with Empower/Chromeleon.

Responsibilities

• Develop, validate, and transfer analytical methods for raw materials, intermediates, and finished products per ICH guidelines.
• Perform routine and non-routine testing of pharmaceutical samples using HPLC, UPLC, GC, UV-Vis, FTIR, and KF titration.
• Operate and maintain analytical instrumentation, ensuring proper calibration and performance.
• Investigate out-of-specification results and deviations; propose corrective actions.
• Analyze and interpret analytical data; generate comprehensive reports for regulatory submissions and internal use.
• Troubleshoot analytical methods and instrumentation issues.
• Stay updated on GMP and regulatory requirements and industry best practices.
• Collaborate with R&D, manufacturing, and quality assurance.
• Mentor junior analytical chemists and provide technical guidance.
• Contribute to process improvement within the analytical department.

Skills

Analytical chemistry

GMP compliance

Data analysis

Method validation

Instrument troubleshooting

Education

MSc/PhD Analytical Chemistry

Tools

Empower

Chromeleon

Job description

Placements24 is seeking a Senior Analytical Chemistry Specialist to join its quality control and research division in Nelspruit, Mpumalanga. You will develop, validate, and execute analytical methods to ensure the quality, purity, and stability of pharmaceutical products and raw materials.

You will work with HPLC, GC, UV-Vis, FTIR, KF titration, and regulatory-compliant method validation, mentor junior chemists, and contribute to process improvements in a GMP environment.