Remote Senior Computational Chemist - Drug Discovery

Placements24; South Africa; Remote; ZAR 1.200.000 - 1.800.000; Vollzeit

Zusammenfassung

Placements24 seeks a Remote Senior Computational Chemist to join its drug discovery team. You will lead computational design, virtual screening, and structure-based optimization, collaborating with medicinal chemists and biologists to accelerate therapeutic candidates.

The role emphasizes standalone work in a fully remote setup, with a focus on advanced modeling, data analysis, and effective communication of complex results to cross-functional teams and publications.

Qualifikationen

• Ph.D. in Computational Chemistry, Cheminformatics, or related field with a strong focus on computational drug discovery.
• Minimum of 6 years of experience in computational chemistry applied to drug discovery.
• Proficiency in computational chemistry software packages (e.g., Schrodinger, MOE, AutoDock, GROMACS).
• Strong programming skills in Python and experience with cheminformatics toolkits (e.g., RDKit, OpenBabel).
• Experience with molecular dynamics simulations and free energy calculations.
• Excellent data analysis and visualization skills.

Aufgaben

• Apply computational chemistry methods to drug discovery projects, including MD and QM.
• Perform virtual screening and docking studies to identify drug candidates.
• Conduct structure-based and ligand-based drug design and pharmacophore modeling.
• Develop cheminformatics tools and databases for library analysis and property prediction.
• Collaborate with medicinal chemists to guide design and synthesis of compounds.
• Analyze large datasets from simulations and assays and communicate findings.

Kenntnisse

Python

Data analysis

Remote work

Ausbildung

Ph.D. in Computational Chemistry, Cheminformatics, or related field

Tools

Schrodinger

MOE

AutoDock

GROMACS

RDKit

OpenBabel

Jobbeschreibung

Placements24 seeks a Remote Senior Computational Chemist to join its drug discovery team. You will lead computational design, virtual screening, and structure-based optimization, collaborating with medicinal chemists and biologists to accelerate therapeutic candidates.

The role emphasizes standalone work in a fully remote setup, with a focus on advanced modeling, data analysis, and effective communication of complex results to cross-functional teams and publications.