Remote Lead Drug Discovery Scientist (Small Molecules)

Placements24; Mossel Bay; Hybrid; ZAR 1,200,000 - 2,100,000; Full time

Benefits offered by this job

Remote work

Health insurance

Stock options

Home office allowance

Professional development

Retirement plan

Job summary

Placements24 is seeking a Remote Lead Research Scientist to drive early drug discovery for a global pharmaceutical leader. You will lead a team in designing and evaluating novel small molecule candidates and guide strategy with rigorous scientific standards.

This fully remote role requires cross‑functional collaboration, CRO oversight, and clear scientific communication. A PhD with 8+ years in medicinal chemistry and DMPK is essential to deliver results from a home office.

Qualifications

• PhD in Organic Chemistry, Medicinal Chemistry, Pharmacology, or related field.
• 8+ years of pharmaceutical R&D experience with small molecule discovery.
• Strong knowledge of medicinal chemistry, DMPK, and early-stage development.
• Proven leadership of research projects and teams.
• Excellent communication and remote collaboration skills.

Responsibilities

• Lead design and synthesis of small molecule drug candidates.
• Oversee early-stage drug discovery including in vitro and in vivo studies.
• Develop lead optimization strategies focusing on potency and DMPK.
• Collaborate with biologists, toxicologists, and formulation scientists.
• Mentor junior researchers and manage CRO partnerships.
• Prepare research reports, regulatory documents, and contribute to patents.
• Present findings to senior management and scientific boards.

Skills

Leadership

Strategic thinking

Remote teamwork

Scientific writing

Education

PhD in Organic/Medicinal Chemistry

Job description

Placements24 is seeking a Remote Lead Research Scientist to drive early drug discovery for a global pharmaceutical leader. You will lead a team in designing and evaluating novel small molecule candidates and guide strategy with rigorous scientific standards.

This fully remote role requires cross‑functional collaboration, CRO oversight, and clear scientific communication. A PhD with 8+ years in medicinal chemistry and DMPK is essential to deliver results from a home office.