Process Development Scientist

Placements24; Upington; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Competitive salary

Performance incentives

Medical benefits

Retirement benefits

Professional development

Industry workshops

Modern lab facilities

Relocation assistance

Job summary

Placements24 in Upington is seeking a Process Development Scientist to optimize and scale manufacturing processes for pharmaceutical intermediates and APIs. You will apply chemical engineering and synthetic chemistry to design, develop, and validate robust production processes.

The role involves scale-up from lab to pilot and commercial scale, development of analytical methods, and technology transfer, with emphasis on yield, purity, and cost efficiency.

Qualifications

• Master's or PhD in a relevant field
• Minimum 3 years in process development in pharma or fine chemicals
• Strong understanding of organic synthesis and reaction kinetics
• Experience with process scale-up, tech transfer, and GMP environments
• Proficiency in analytical techniques such as HPLC, GC, NMR, and MS

Responsibilities

• Design, develop, and optimize chemical synthesis routes and manufacturing processes for pharmaceutical intermediates and APIs
• Conduct process development studies, including route scouting, reaction optimization, and purification strategies
• Perform scale-up activities from laboratory to pilot plant and commercial manufacturing scales, ensuring process robustness and safety
• Develop and validate analytical methods required for process monitoring and control
• Troubleshoot manufacturing process issues and implement effective solutions to improve yield, purity, and efficiency
• Prepare detailed process development reports, batch records, and technology transfer documentation

Skills

Process development

Organic synthesis

Analytical methods

Scale-up

GMP experience

Experimental design

Education

Master's or PhD in Chemistry/ Chemical Engineering/ Pharmaceutical Sciences

Tools

HPLC

GC

NMR

Mass spectrometry

Job description

About the Role

Our client is seeking a talented Process Development Scientist to join their innovative team in Upington . This role is central to optimizing and scaling up manufacturing processes for pharmaceutical intermediates and active pharmaceutical ingredients (APIs). You will apply chemical engineering principles and synthetic chemistry expertise to design, develop, and validate robust, efficient, and cost-effective production processes. This position offers a unique chance to contribute to the efficient manufacturing of essential pharmaceutical components in a growing industrial area.

Key Responsibilities

• Design, develop, and optimize chemical synthesis routes and manufacturing processes for pharmaceutical intermediates and APIs.
• Conduct process development studies, including route scouting, reaction optimization, and purification strategies.
• Perform scale-up activities from laboratory to pilot plant and commercial manufacturing scales, ensuring process robustness and safety.
• Develop and validate analytical methods required for process monitoring and control.
• Troubleshoot manufacturing process issues and implement effective solutions to improve yield, purity, and efficiency.
• Prepare detailed process development reports, batch records, and technology transfer documentation.

Requirements

• Master's or Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Sciences, or a related field.
• Minimum of 3 years of experience in process development within the pharmaceutical or fine chemical industry.
• Strong understanding of organic synthesis, reaction kinetics, and chemical engineering principles.
• Experience with process scale-up, technology transfer, and GMP manufacturing environments.
• Proficiency in analytical techniques such as HPLC, GC, NMR, and mass spectrometry.
• Excellent problem-solving abilities, strong experimental design skills, and effective communication.

Benefits

• Competitive annual salary and performance-based incentives.
• Comprehensive medical, retirement, and other employee benefits.
• Opportunities for professional development, training, and participation in industry workshops.
• Access to modern laboratory and pilot plant facilities.
• Relocation assistance may be provided for suitable candidates.
• A challenging and rewarding career opportunity in process innovation in Upington .