Principal Research Scientist (Biotechnology)

Placements24; Klerksdorp; Hybrid; ZAR 1,400,000 - 2,400,000; Full time

Benefits offered by this job

Competitive compensation

Health Insurance

Professional development

Relocation assistance

Generous PTO

Cutting‑edge facilities

Job summary

Placements24 in Klerksdorp is seeking a highly accomplished Principal Research Scientist to lead innovative life sciences projects. You will guide teams across genetic engineering, therapeutic protein development, and molecular diagnostics, with a hybrid work model and significant facility presence in Klerksdorp.

The role requires a Ph.D. with 8+ years of post‑doctoral or equivalent experience, a strong publication record, and demonstrated leadership in research strategy and execution.

Qualifications

• Ph.D. in a life science discipline.
• Minimum of 8 years post‑doctoral or equivalent industry research experience.
• Demonstrated independent research leadership with publications in high‑impact journals.
• Extensive experience with molecular biology techniques, cell culture, and protein expression/purification.
• Strong leadership, communication and mentoring skills; able to manage projects.

Responsibilities

• Lead and design complex research projects in gene editing, synthetic biology, or protein engineering.
• Develop and implement cutting‑edge experimental methodologies and protocols.
• Oversee laboratory operations, ensuring rigor, safety standards and QC.
• Analyze and interpret complex data, drawing robust conclusions and next steps.
• Mentor and guide junior scientists and research staff.
• Collaborate with cross‑functional teams including clinical, regulatory, and product development.
• Publish papers, contribute to patents and grant proposals.
• Present findings at internal meetings and external conferences.
• Stay updated on latest scientific advancements and technologies.
• Manage project timelines, resources, and budgets.

Skills

Leadership

Communication

Mentoring

Team collaboration

Project management

Statistical analysis

Scientific writing

Education

Ph.D. in Molecular Biology, Biotechnology, Biochemistry, Genetics, or related life science

Job description

About the Role

Our client, a visionary biotechnology firm at the cutting edge of life sciences research, is actively seeking a highly accomplished Principal Research Scientist to lead innovative projects in Klerksdorp, North West, ZA . This senior position is critical for driving discovery and development in areas such as genetic engineering, therapeutic protein development, and advanced molecular diagnostics. The ideal candidate will possess a deep scientific understanding, extensive hands‑on laboratory experience, a strong publication record, and demonstrated leadership capabilities. You will guide research teams, conceptualize novel experimental strategies, and contribute significantly to the company’s scientific vision and pipeline advancement. This role presents a unique opportunity to shape the future of biotechnology, working with state‑of‑the‑art facilities and collaborating with a world‑class team of scientists and researchers. Our client is committed to fostering a dynamic, innovative, and collaborative research culture.

Key Responsibilities

• Lead and design complex research projects in areas such as gene editing, synthetic biology, or protein engineering.
• Develop and implement cutting‑edge experimental methodologies and protocols.
• Oversee laboratory operations, ensuring adherence to scientific rigor, safety standards, and quality control.
• Analyze and interpret complex experimental data, drawing robust conclusions and formulating next steps.
• Mentor and guide junior scientists and research associates, fostering their technical development and scientific growth.
• Collaborate effectively with cross‑functional teams, including clinical, regulatory, and product development groups.
• Author and contribute to scientific publications, patent applications, and grant proposals.
• Present research findings at internal meetings and external scientific conferences.
• Stay abreast of the latest scientific advancements and emerging technologies in the biotechnology field.
• Manage project timelines, resources, and budgets effectively.

Requirements

• Ph.D. in Molecular Biology, Biotechnology, Biochemistry, Genetics, or a related life science discipline.
• A minimum of 8 years of post‑doctoral or equivalent industry research experience in a relevant field.
• Demonstrated track record of independent research leadership, including significant publications in high‑impact journals.
• Extensive experience with molecular biology techniques, cell culture, protein expression/purification, or advanced analytical methods.
• Proven ability to conceptualize and execute complex research strategies.
• Strong understanding of experimental design and statistical analysis.
• Excellent leadership, communication, and interpersonal skills.
• Ability to work effectively in a fast‑paced, collaborative research environment.
• Experience in managing research projects and mentoring staff is essential.
• This role requires a hybrid work model, with a significant presence in our Klerksdorp facility.

Benefits

• Our client offers a highly competitive compensation package, including a substantial base salary and performance‑driven bonuses.
• Comprehensive health, dental, and vision insurance are provided, alongside a robust retirement savings plan with employer matching.
• We support continuous professional development through funding for conferences, workshops, and further education.
• Relocation assistance may be available for qualified candidates moving to the Klerksdorp area.
• We promote a healthy work‑life balance with generous paid time off.
• Our client provides access to cutting‑edge research infrastructure and fosters an intellectually stimulating work environment.