Principal Research Scientist - Biotechnology

Placements24; Johannesburg; Hybrid; ZAR 1,800,000 - 2,400,000; Full time

Benefits offered by this job

Hybrid work model

Health insurance

Retirement contributions

Job summary

Placements24 is recruiting on behalf of a leading biotechnology research institution in Johannesburg, Gauteng. We seek a Principal Research Scientist to lead groundbreaking projects, mentor junior staff, and drive the development of novel therapeutic solutions.

The candidate will maintain an exceptional publication record and manage cross-functional teams within a dynamic research environment. The role emphasizes strategic project leadership, data-driven experimentation, and collaboration across

Qualifications

• PhD in Molecular Biology, Cell Biology, Biochemistry, or related field.
• 8–10 years of postdoc/research experience in biotech or drug discovery.
• Proven leadership and team supervision experience.
• Strong publication record in high-impact journals.
• Experience securing research funding is desirable.
• Excellent communication and interpersonal skills.
• Ability to work in a multidisciplinary team.

Responsibilities

• Lead and manage complex research projects from conception to completion.
• Design, execute, analyze experiments; interpret results.
• Mentor postdocs, research associates, and technicians.
• Publish in peer‑reviewed journals and present at conferences.
• Contribute to grant writing and secure external funding.
• Collaborate with medicinal chemistry, pharmacology, and clinical development.
• Ensure safety, ethics, and institutional policy compliance.

Skills

Scientific leadership

Project management

Data analysis

Communication

Mentorship

Multidisciplinary collaboration

Education

PhD in Molecular Biology / Cell Biology / Biochemistry or related field

Tools

Bioinformatics tools

Job description

About the Role

Our client, a leading research and development institution at the forefront of biotechnology innovation, is seeking an exceptional Principal Research Scientist to join their state-of-the-art facility in Johannesburg, Gauteng . This senior position offers a unique opportunity for a highly accomplished scientist to lead groundbreaking research projects, mentor junior staff, and contribute significantly to the development of novel therapeutic solutions. The ideal candidate will possess a strong publication record, extensive experience in molecular biology, cell biology, or a related field, and a proven ability to manage complex research programs. You will play a pivotal role in shaping the future of biotechnology and driving scientific discovery within a collaborative and dynamic research environment.

Key Responsibilities

• Lead and manage complex research projects from conception to completion, ensuring scientific rigor and adherence to timelines and budgets.
• Design and execute experiments, analyze data, and interpret results to advance understanding in key areas of biotechnology.
• Develop and optimize novel research methodologies and protocols.
• Mentor and guide a team of postdoctoral researchers, research associates, and technicians, fostering a collaborative and productive research atmosphere.
• Author high-impact scientific publications in peer-reviewed journals and present findings at international conferences.
• Contribute to grant writing and secure external funding to support research initiatives.
• Collaborate with cross-functional teams, including medicinal chemistry, pharmacology, and clinical development, to integrate research findings into drug discovery and development programs.
• Stay abreast of the latest scientific advancements, emerging technologies, and competitor activities in the field.
• Ensure compliance with all safety regulations, ethical guidelines, and institutional policies.

Requirements

• Ph.D. in Molecular Biology, Cell Biology, Biochemistry, or a closely related discipline from a reputable institution.
• A minimum of 8-10 years of post-doctoral research experience in an academic or industry setting, with a strong focus on biotechnology or drug discovery.
• Proven track record of scientific leadership, including project management and team supervision.
• Extensive experience in experimental design, data analysis, and interpretation using advanced techniques (e.g., genomics, proteomics, high-throughput screening, bioinformatics).
• A substantial publication record in high-impact peer-reviewed journals.
• Demonstrated success in securing research grants or funding is highly desirable.
• Excellent communication, presentation, and interpersonal skills, with the ability to effectively convey complex scientific information.
• Proficiency in relevant scientific software and databases.
• Ability to work collaboratively in a multidisciplinary team environment.

Benefits

• Our client offers a highly competitive salary commensurate with experience and qualifications, along with an attractive benefits package including comprehensive health insurance, retirement contributions, and performance-related bonuses.
• You will have the opportunity to work on cutting-edge research projects in a stimulating environment.
• Professional development and continued learning are strongly encouraged.
• This role offers a hybrid work model, providing flexibility while ensuring vital in-person collaboration at our Johannesburg facility.
• Be part of a world-class team making significant contributions to human health in Gauteng.