Lead Molecular Biologist - Gene Editing Technologies

Placements24; Cape Town; On-site; ZAR 1,800,000 - 2,400,000; Full time

Benefits offered by this job

Highly competitive salary and bonuses

Medical, dental, and vision insurance

Stock options and long-term incentives

Career growth and leadership deve lopm

Access to advanced lab equipment in CT

Professional development incl. conf.

Relocation assistance may be available

Work on transformative therapies

Job summary

Placements24 in Cape Town seeks a Lead Molecular Biologist to spearhead gene editing R&D. You will lead a research team, shape strategy for CRISPR-Cas9 therapies, and drive projects from conception to preclinical validation in a fast‑paced biotech environment.

The role requires a PhD and 7+ years post‑doc experience with leadership, extensive hands-on molecular biology skills, and a track record in publications.

Qualifications

• PhD in Molecular Biology, Genetics, Biochemistry, or related field.
• 7+ years post‑doctoral research, with ≥3 years in leadership.
• Extensive hands‑on experience with gene editing (CRISPR/Cas9, etc.).
• Proficiency in molecular biology techniques: PCR, qPCR, Western blot, cloning, cell culture, flow cytometry.
• Experience with NGS data analysis is desirable.

Responsibilities

• Lead and mentor a team of molecular biologists and research associates focused on gene editing applications.
• Develop and optimize protocols for gene editing using CRISPR, TALENs, and other emerging technologies.
• Design and execute experiments to assess efficacy, specificity, and safety of gene editing strategies.
• Analyze and interpret complex experimental data, including next-generation sequencing results.
• Collaborate with cross‑functional teams including geneticists, pharmacologists, and regulatory affairs specialists.
• Manage project timelines, resources, and budgets effectively.
• Contribute to the preparation of scientific publications, patent applications, and regulatory submissions.
• Represent the company at scientific conferences and foster external collaborations.
• Ensure compliance with all relevant safety and ethical guidelines in research.

Skills

Leadership

Communications

Project management

Education

PhD in Molecular Biology or related field

Tools

CRISPR/Cas9

TALENs

NGS data analysis

PCR & qPCR

Flow cytometry

Job description

About the Role

Our client, a pioneering biotechnology firm located in the vibrant city of Cape Town, Western Cape , is seeking an experienced and visionary Lead Molecular Biologist to spearhead research in cutting-edge gene editing technologies. This is a critical leadership role within our Scientific Research & Development department, focused on exploring and applying novel approaches like CRISPR-Cas9 for therapeutic development. The successful candidate will be instrumental in shaping the research strategy, managing a team of talented scientists, and driving projects from conception through to preclinical validation. You will be at the forefront of innovation, working with state-of-the‑art equipment and collaborating with world‑class researchers. This position offers an unparalleled opportunity to contribute to the advancement of gene therapy and influence the future of medicine. The role requires a deep understanding of molecular mechanisms, a passion for discovery, and the ability to lead and inspire a research team in a demanding scientific environment. Join us in Cape Town and make a lasting impact.

Key Responsibilities

• Lead and mentor a team of molecular biologists and research associates focused on gene editing applications.
• Develop and optimize protocols for gene editing using CRISPR, TALENs, and other emerging technologies.
• Design and execute experiments to assess the efficacy, specificity, and safety of gene editing strategies.
• Analyze and interpret complex experimental data, including next-generation sequencing results.
• Collaborate with cross‑functional teams including geneticists, pharmacologists, and regulatory affairs specialists.
• Manage project timelines, resources, and budgets effectively.
• Contribute to the preparation of scientific publications, patent applications, and regulatory submissions.
• Represent the company at scientific conferences and foster external collaborations.
• Ensure compliance with all relevant safety and ethical guidelines in research.

Requirements

• Ph.D. in Molecular Biology, Genetics, Biochemistry, or a closely related field.
• Minimum of 7 years of post‑doctoral research experience, with at least 3 years in a leadership or senior scientist role.
• Extensive hands‑on experience with gene editing technologies (CRISPR/Cas9, etc.) and their applications.
• Proficiency in a broad range of molecular biology techniques (e.g., PCR, qPCR, Western blotting, cloning, cell culture, flow cytometry).
• Strong understanding of molecular mechanisms of disease and therapeutic intervention.
• Experience with next‑generation sequencing (NGS) data analysis is highly desirable.
• Demonstrated ability to lead and manage research projects and personnel.
• Excellent written and oral communication skills, with a track record of publications.
• Ability to thrive in a fast‑paced, innovative R&D environment in Cape Town .

Benefits

• Highly competitive salary and performance‑based bonuses.
• Comprehensive medical, dental, and vision insurance plans.
• Generous stock options and long‑term incentive plans.
• Significant opportunities for career growth and leadership development.
• Access to advanced laboratory equipment and facilities in Cape Town .
• Support for professional development, including conference attendance.
• Relocation assistance may be available for qualified candidates.
• Work on transformative therapies that could change patient lives.