Senior Genomics Scientist (CRISPR Technology)

Placements24; Mossel Bay; Hybrid; ZAR 1.200.000 - 1.800.000; Vollzeit

Benefits dieser Stelle

Competitive salary

Medical, dental, and vision insurance

Stock options

Professional development budget

Remote-friendly environment

Generous paid time off

Zusammenfassung

Placements24 in Mossel Bay, Western Cape, is seeking a Senior Genomics Scientist with CRISPR expertise to design and execute cutting-edge gene editing experiments. The role offers remote work flexibility and collaboration with a diverse team on therapeutic and diagnostic projects.

You will lead CRISPR-Cas9 strategies, perform NGS-based analysis, and contribute to publication-ready reports while advancing genomic science in a dynamic biotech environment.

Qualifikationen

• PhD in Molecular Biology, Genetics, Genomics, or related field.
• 5+ years post-doc or industry experience in genomics and gene editing.
• Hands-on CRISPR-Cas9 experience and other gene editing tools.
• Strong molecular biology techniques: NGS library prep, PCR, qPCR, cell culture.

Aufgaben

• Design and implement CRISPR/Cas9 gene editing strategies for various cells and models.
• Develop and optimize gene editing protocols including gRNA design and delivery methods.
• Perform high-throughput screening to identify gene functions.
• Use NGS technologies for genomic analysis, including variant calling.
• Analyze complex genomic data with bioinformatics and stats.
• Collaborate with internal and external teams on research projects.
• Prepare reports, presentations, and manuscripts for dissemination.
• Stay updated with CRISPR and genomics advancements.

Kenntnisse

CRISPR-Cas9

Genomics analysis

Statistical analysis

Problem solving

Teamwork

Remote collaboration

Ausbildung

PhD in Molecular Biology/Genomics

Tools

NGS data analysis tools

Jobbeschreibung

About the Role

Our client, a leader in genetic engineering and biotechnology, is seeking a highly motivated Senior Genomics Scientist with expertise in CRISPR technology. This position is based in Mossel Bay, Western Cape, and offers a remote work option. You will be instrumental in designing and executing experiments utilizing advanced CRISPR-based tools for gene editing and functional genomics studies. Your work will contribute to the development of novel therapeutics and diagnostic tools. This role requires a deep understanding of molecular biology, genomics, and gene editing principles, coupled with strong analytical and problem-solving skills. You will collaborate with a talented team of scientists and researchers to push the boundaries of genetic innovation.

Key Responsibilities

• Design and implement CRISPR/Cas9 gene editing strategies for various cell types and model systems.
• Develop and optimize protocols for gene editing, including gRNA design, delivery methods, and off-target analysis.
• Perform high-throughput screening assays to identify and characterize gene functions.
• Utilize next-generation sequencing (NGS) technologies for genomic analysis, including variant calling and mutation detection.
• Analyze and interpret complex genomic datasets using bioinformatics tools and statistical methods.
• Troubleshoot experimental challenges and provide solutions to ensure project success.
• Collaborate with internal teams and external partners on research projects.
• Prepare detailed reports, presentations, and manuscripts for scientific dissemination.
• Stay current with the latest advancements in CRISPR technology and genomics.

Requirements

• PhD in Molecular Biology, Genetics, Genomics, or a related field.
• Minimum of 5 years of post-doctoral or industry experience in genomics and gene editing.
• Proven hands-on experience with CRISPR-Cas9 technology and other gene editing tools.
• Strong knowledge of molecular biology techniques, including NGS library preparation, PCR, qPCR, and cell culture.
• Experience with bioinformatics tools and software for genomic data analysis.
• Proficiency in statistical analysis of biological data.
• Excellent problem-solving abilities and attention to detail.
• Strong communication and teamwork skills, essential for remote collaboration.
• Ability to manage multiple projects and prioritize tasks effectively.

Benefits

• Competitive salary and bonus structure.
• Comprehensive medical, dental, and vision insurance.
• Stock options and other long-term incentives.
• Generous budget for professional development and conference attendance.
• Opportunity to work with cutting-edge technologies in gene editing and genomics.
• Flexible remote work environment.
• Collaborative and innovative research culture.
• Generous paid time off.