Lead Gene Editing Scientist

Placements24; Cape Town; Presencial; ZAR 1.800.000 - 3.200.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Competitive salary

Health insurance

Relocation assistance

Descripción de la vacante

Placements24 is seeking a Lead Gene Editing Scientist for our Cape Town facility. You will lead a research team focused on developing novel gene editing technologies for therapeutic applications, guiding discovery through preclinical validation.

The role demands strategic direction for the R&D pipeline, hands-on expertise in CRISPR, TALENs and ZFNs, and a track record of delivering high-quality scientific outcomes in a collaborative lab environment.

Formación

• PhD in Genetics, Molecular Biology, Genomics or closely related field with gene editing emphasis.
• 7+ years leading research projects and managing scientific teams.
• Expertise with gene editing tools including CRISPR, TALENs and ZFNs.
• Proficiency with bioinformatics sequence analysis, gRNA design and off-target prediction.
• Experience developing and validating assays for editing efficiency and specificity.

Responsabilidades

• Lead and manage a team of scientists and technicians in gene editing research.
• Design, implement and optimize gene editing strategies (CRISPR-Cas9) for target manipulation.
• Oversee planning and execution of experiments with robust designs.
• Analyze genetics and phenotypic data to inform research plans.
• Manage project timelines, resources and budgets to milestones.
• Prepare and review publications, patents and regulatory submissions.

Conocimientos

Leadership

Mentorship

Project management

Bioinformatics

Educación

Ph.D. in Genetics / Molecular Biology / Genomics

Herramientas

CRISPR/TALENs/ZFN toolkit

Bioinformatics tools

Descripción del empleo

About the Role

Our client is seeking a highly motivated and experienced Lead Gene Editing Scientist to spearhead groundbreaking research initiatives in their Cape Town facility. This senior position offers the opportunity to lead a team of dedicated researchers focused on developing novel gene editing technologies for therapeutic applications. You will play a crucial role in shaping the strategic direction of our R&D pipeline, driving innovation from discovery to preclinical validation. This is a fully on-site role, designed for individuals passionate about advancing genetic medicine and contributing to significant scientific advancements in a collaborative laboratory setting.

Key Responsibilities

• Lead and manage a team of scientists and technicians involved in gene editing research, providing scientific direction and mentorship.
• Design, implement, and optimize innovative gene editing strategies (e.g., CRISPR-Cas9) for target gene manipulation in various cell types and disease models.
• Oversee the planning and execution of experiments, ensuring high-quality data generation and robust experimental design.
• Analyze and interpret complex genetic and phenotypic data, translating findings into actionable research plans.
• Manage project timelines, resources, and budgets effectively to meet research milestones.
• Author and review scientific publications, patents, and regulatory submissions related to gene editing technologies.

Requirements

• Ph.D. in Genetics, Molecular Biology, Genomics, or a closely related field with a strong emphasis on gene editing techniques.
• Demonstrated experience (7+ years) in leading research projects and managing scientific teams, preferably within the biotechnology or pharmaceutical industry.
• Expertise in various gene editing tools and methodologies, including CRISPR, TALENs, and ZFNs, with a deep understanding of their applications and limitations.
• Proficiency in bioinformatics tools for sequence analysis, gRNA design, and off-target prediction.
• Proven ability to develop and validate novel assays for assessing gene editing efficiency and specificity.

Benefits

• Highly attractive salary package commensurate with experience.
• Comprehensive health insurance, including medical, dental, and vision coverage.
• Opportunities for professional growth and leadership development within a leading R&D organization.
• Access to state-of-the-arts research facilities and advanced genomic technologies.
• Relocation assistance available for qualified candidates moving to Cape Town.