Formulation Scientist - Oral Solid Dosage

Placements24; Mossel Bay; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Competitive salary

Medical, dental, and vision insurance

Generous paid time off

Professional development

R&D environment

Job summary

Placements24 seeks an experienced Formulation Scientist specializing in oral solid dosage forms to lead development from concept to scale-up in Mossel Bay. You will drive innovative formulations meeting regulatory standards and patient needs while collaborating with analytical, process development and manufacturing teams.

The role offers opportunities to work with advanced technologies in a growing pharmaceutical company, with responsibilities spanning project leadership, experimental design,

Qualifications

• Master's or Ph.D. in Pharmaceutical Sciences or related discipline.
• Minimum of 5 years in pharmaceutical formulation development focusing on OSDs.
• Experience with drug delivery, excipient selection, and solid dosage manufacturing.
• Hands-on experience with formulation development equipment and analytical techniques.
• Familiarity with FDA/EMA regulatory guidelines.

Responsibilities

• Design and develop novel oral solid dosage formulations (tablets, capsules).
• Conduct pre-formulation studies on drug-excipient compatibility.
• Optimize formulation parameters and processes for scale-up and manufacturing.
• Perform experiments using lab equipment such as tablet presses and dissolution testers.
• Prepare development reports and documentation for regulatory submissions.
• Collaborate with analytical development, process development, and manufacturing teams.

Skills

Pharmaceutical formulation

Oral solid dosage

Regulatory knowledge

Analytical techniques

Problem-solving

Education

MSc or PhD in Pharmaceutical Sciences or related

Tools

Tablet presses

Capsule fillers

Dissolution testers

Job description

About the Role

Our client is seeking an experienced Formulation Scientist specializing in Oral Solid Dosage (OSD) forms to join their research and development team in Mossel Bay . This role is critical for the development of innovative and robust pharmaceutical formulations that meet regulatory standards and patient needs. You will lead formulation development projects from concept to scale-up, ensuring the successful transition of products into manufacturing. This is an exciting opportunity to work with advanced technologies and contribute to the pipeline of a growing pharmaceutical company.

Key Responsibilities

• Design and develop novel oral solid dosage formulations (tablets, capsules) considering factors like bioavailability, stability, and manufacturability.
• Conduct pre-formulation studies to understand drug-excipient compatibility and material properties.
• Optimize formulation parameters and manufacturing processes for scale-up and commercial production.
• Perform experiments using laboratory equipment such as tablet presses, capsule fillers, and dissolution testers.
• Write detailed development reports, protocols, and documentation required for regulatory submissions.
• Collaborate effectively with analytical development, process development, and manufacturing teams.

Requirements

• Master's or Ph.D. in Pharmaceutical Sciences, Chemical Engineering, or a related discipline.
• Minimum of 5 years of experience in pharmaceutical formulation development, with a strong focus on oral solid dosage forms.
• Expertise in drug delivery systems, excipient selection, and the principles of solid dosage manufacturing.
• Hands-on experience with formulation development equipment and analytical techniques.
• Familiarity with regulatory guidelines relevant to drug product development and submission (e.g., FDA, EMA).
• Strong problem-solving abilities and a scientific approach to formulation challenges.

Benefits

• Competitive salary and potential for annual bonuses.
• Comprehensive medical, dental, and vision insurance.
• Generous paid time off and holiday schedule.
• Opportunities for professional development and conference attendance.
• A supportive and innovative R&D environment.