Fermentation Engineer - Scale-Up Bioprocess (Hybrid)

Placements24

Gauteng

Hybrid

ZAR 600,000 - 900,000

Full time

2 days ago

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Benefits offered by this job

Hybrid work model

Professional development

State-of-the-art facilities

Job summary

Placements24 in South Africa seeks a Bioprocess Engineer specialized in fermentation to join our team in Tembisa. You will optimize and scale biomanufacturing processes for biologics, balancing hands-on lab work with process design. The role requires a degree in chemical/biochemical engineering, 3+ years in industrial bioprocessing, and GMP/DoE experience. Hybrid work offered with development opportunities and modern facilities.

Qualifications

Bachelor's or Master's degree in Chemical Engineering, Biochemical Engineering, or a related field.
Minimum of 3 years of industrial bioprocess engineering experience with fermentation.
Hands-on bioreactor operation, aseptic technique, and process scale-up.
Proficiency in DoE and statistical analysis for process optimization.
Familiarity with GMP and biopharma regulatory requirements.
Strong problem-solving and teamwork skills.

Responsibilities

Design, optimize, and scale-up fermentation processes for microbial and mammalian cell cultures.
Monitor and control critical process parameters to ensure optimal cell growth, product formation, and downstream processing compatibility.
Conduct root cause analysis for process deviations and implement corrective and preventative actions (CAPAs).
Collaborate with upstream and downstream teams to ensure seamless integration of fermentation with other biomanufacturing stages.
Develop and validate new process analytical technology (PAT) tools for real-time monitoring and control of fermentation.
Generate detailed batch records, technical reports, and process documentation.