Clinical Pharmacologist

Placements24; Mossel Bay; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Health insurance

Retirement contributions

Annual performance bonus

Paid time off

Job summary

Placements24 is seeking an accomplished Clinical Pharmacologist for a fully remote role. You will design and oversee clinical pharmacology studies, focusing on early-phase trials, PK/PD data analysis, and regulatory submissions.

The ideal candidate has 6+ years in clinical pharmacology, strong GCP knowledge, and excellent publication track record. Independent, self-disciplined professionals will thrive in our remote-first environment.

Qualifications

• Minimum of 6 years of experience in clinical pharmacology research in pharma/biotech.
• Strong design and management experience of Phase I trials.
• In-depth knowledge of PK/PD modeling and simulation.
• GCP and regulatory requirements for clinical drug development.
• Excellent analytical and communication skills.
• Experience publishing scientific work.

Responsibilities

• Design, plan, and execute clinical pharmacology studies including Phase I.
• Develop study protocols, investigator brochures, and informed consent forms.
• Oversee study conduct ensuring GCP and regulatory compliance.
• Analyze PK/PD data and interpret results.
• Collaborate with statisticians to ensure data integrity and timely analysis.
• Prepare clinical study reports and regulatory submission documents.
• Provide expert input on drug development strategy.
• Liaise with investigators and site personnel.
• Stay current with pharmacology advancements and biomarkers.

Education

MD or PhD in Pharmacology / Clinical Pharmacology

Tools

Phoenix WinNonlin

R

Job description

About the Role

Our client, a pioneering pharmaceutical research organization, is seeking an accomplished Clinical Pharmacologist to contribute to their groundbreaking research initiatives. This fully remote position offers the flexibility to work from anywhere, focusing on the investigation of drug action in humans. You will be responsible for designing and overseeing clinical pharmacology studies, analyzing pharmacokinetic and pharmacodynamic data, and contributing to the development of new medicines. This role is ideal for an experienced pharmacologist who thrives in an independent, results-oriented environment. As a remote-first organization, all collaboration and project management are conducted digitally, making strong communication and self-discipline paramount. The opportunity to significantly impact drug development from a distance is immense. The initial focus will be on early-phase clinical trials, assessing drug safety, tolerability, and efficacy in target patient populations. This is a chance to join a forward-thinking company shaping the future of medicine.

Key Responsibilities

• Design, plan, and execute clinical pharmacology studies, including Phase I trials.
• Develop study protocols, investigator brochures, and informed consent forms.
• Oversee study conduct, ensuring adherence to GCP, ethical principles, and regulatory requirements.
• Analyze pharmacokinetic (PK) and pharmacodynamic (PD) data, and interpret results.
• Collaborate with statisticians and data managers to ensure data integrity and timely analysis.
• Prepare clinical study reports, regulatory submission documents, and scientific publications.
• Provide expert advice on drug development strategy and clinical pharmacology.
• Liaise with key opinion leaders, investigators, and site personnel.
• Stay current with advancements in clinical pharmacology, drug metabolism, and pharmacogenomics.
• Contribute to the selection of appropriate biomarkers and endpoints for clinical studies.

Requirements

• M.D. or Ph.D. in Pharmacology, Clinical Pharmacology, Pharmacy, or a related medical science.
• Minimum of 6 years of relevant experience in clinical pharmacology research within the pharmaceutical or biotechnology industry.
• Demonstrated experience in designing and managing Phase I clinical trials.
• In-depth knowledge of PK/PD modeling and simulation techniques.
• Strong understanding of GCP and regulatory requirements for clinical drug development.
• Excellent analytical, problem-solving, and critical thinking skills.
• Exceptional written and verbal communication skills, with a proven ability to publish scientific work.
• Proficiency in relevant software for data analysis (e.g., Phoenix WinNonlin, R).
• Ability to work independently and manage projects effectively in a remote setting.
• Medical license is a plus.

Benefits

• This remote position offers a highly competitive salary and a comprehensive benefits package, including excellent health insurance, retirement contributions, and an annual performance bonus.
• Our client is committed to fostering a healthy work-life balance through flexible working arrangements.
• Opportunities for professional growth and engagement in cutting-edge research are abundant.
• Access to the latest scientific literature and research tools.
• Paid time off includes generous vacation, sick leave, and public holidays.
• The company promotes a culture of scientific excellence and innovation.
• This is a unique opportunity to join a leading organization from the comfort of your home, with the potential to be based anywhere in South Africa.