Clinical Pharmacologist - Full-time

Placements24; Noord-Kaap; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Competitive salary

Bonus structure

Health insurance

Retirement savings plan

Paid time off

Conference attendance

Job summary

Placements24 in Kimberley, Northern Cape, ZA is seeking a Clinical Pharmacologist to shape early phase development through design and interpretation of pharmacology studies. You will work within a multidisciplinary team to inform efficacy and safety profiles.

The role emphasizes GCP-compliant trial design, PK/PD modelling, and collaboration with operations, biostatistics, and regulatory affairs to prepare submissions and scientific reports. Experience in pharma/biotech is required.

Qualifications

• MD or PhD in Pharmacology or closely related field.
• Minimum 5 years in clinical pharmacology within pharma/biotech.
• Experience designing and executing early-phase (Phase I/II) trials.
• Strong PK/PD modelling and regulatory familiarity (ICH-GCP).

Responsibilities

• Design and oversee clinical pharmacology study protocols with regulatory compliance.
• Lead PK/PD, DDI studies and early-phase trial execution.
• Analyze data and interpret drug behavior in humans.
• Prepare reports, publications, and regulatory submissions.
• Collaborate with biostatisticians and pharmacokineticists for data analysis.

Skills

PK/PD modeling

ICH-GCP knowledge

Clinical pharmacology

Regulatory reporting

Analytical thinking

Education

MD or PhD in Pharmacology/Clinical Pharmacology

Job description

About the Role

Our client, a leading biopharmaceutical research company, is actively seeking a highly qualified Clinical Pharmacologist to join their drug development team in Kimberley, Northern Cape, ZA. This role is critical for the design, conduct, and interpretation of clinical pharmacology studies that inform drug efficacy and safety profiles. You will contribute to shaping the early phase development of novel therapeutics, working closely with cross-functional teams including clinical operations, biostatistics, and regulatory affairs. This is an exceptional opportunity for an experienced pharmacologist to contribute to life-changing medicines in a dedicated and scientifically rigorous environment.

Key Responsibilities

• Design and develop clinical pharmacology study protocols, ensuring scientific validity and compliance with regulatory requirements.
• Oversee the conduct of clinical pharmacology studies, including pharmacokinetic (PK), pharmacodynamic (PD), and drug-drug interaction (DDI) studies.
• Analyze and interpret clinical pharmacology data, developing sound conclusions regarding drug behavior in humans.
• Prepare scientific reports, publications, and presentations based on clinical pharmacology study results.
• Contribute to regulatory submissions by providing clinical pharmacology expertise and data.
• Collaborate with biostatisticians and pharmacokineticists to ensure appropriate data analysis and interpretation.
• Provide scientific and strategic input into the selection and development of drug candidates.
• Stay abreast of the latest advancements in clinical pharmacology and relevant therapeutic areas.
• Ensure all study activities are conducted in compliance with Good Clinical Practice (GCP) and other applicable regulations.

Requirements

• M.D. or Ph.D. in Pharmacology, Clinical Pharmacology, or a closely related scientific discipline.
• A minimum of 5 years of experience in clinical pharmacology within the pharmaceutical or biotechnology industry.
• Demonstrated experience in designing and executing early-phase clinical trials (Phase I/II).
• Strong understanding of pharmacokinetic/pharmacodynamic (PK/PD) modeling and simulation.
• In-depth knowledge of ICH-GCP guidelines and regulatory requirements for clinical development.
• Excellent analytical, critical thinking, and problem-solving skills.
• Strong scientific writing and presentation abilities.
• Ability to work effectively both independently and as part of a collaborative team in Kimberley, Northern Cape, ZA.

Benefits

• Our client offers a highly competitive salary and bonus structure, commensurate with experience.
• The comprehensive benefits package includes excellent health, dental, and vision insurance, a robust retirement savings plan, and generous paid time off.
• Opportunities for professional growth and development, including attendance at scientific conferences, are readily available.
• You will be working on cutting-edge research and development projects that have the potential to significantly impact patient health from our facilities in Kimberley, Northern Cape, ZA.
• Join a team of dedicated scientists committed to advancing pharmaceutical innovation.