Chemical Engineer - Pharmaceutical Process Development

Placements24; Klerksdorp; Presencial; ZAR 900 000 - 1 300 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Competitive salary

Health insurance

Retirement planning

Performance-based incentives

Training and growth opportunities

Resumo da oferta

Placements24 is seeking a highly skilled Chemical Engineer in Klerksdorp, North West to drive process development for APIs and intermediates. You will design experiments, optimize synthesis routes and scale processes from bench to pilot and full-scale production in a GMP setting.

You will collaborate with R&D, analytical and manufacturing teams, applying reaction engineering, process modeling and DOE to deliver robust, compliant and scalable processes for life-saving medicines.

Qualificações

• Bachelor's or Master's degree in Chemical Engineering.
• 6+ years in pharmaceutical process development or fine chemical manufacturing.
• Strong background in organic chemistry and reaction engineering.
• Experience with process scale-up, technology transfer, and GMP environments.
• Proficiency in process modeling software and DOE / statistical analysis.
• Knowledge of FDA/EMA regulatory guidelines for pharma manufacturing.

Responsabilidades

• Develop and optimize synthesis routes for APIs and intermediates.
• Design and conduct lab experiments for process characterization and validation.
• Scale-up processes from bench to pilot plant and commercial manufacturing.
• Use process modeling and simulation tools to improve efficiency.
• Ensure GMP, regulatory and safety standards are met.
• Collaborate with R&D chemists, analytical scientists and manufacturing.

Conhecimentos

Organic chemistry

Reaction engineering

Process scale-up

GMP environments

DOE / statistical analysis

Cross-functional collaboration

Formação académica

Bachelor's or Master's in Chemical Engineering

Ferramentas

Process simulation software

Descrição da oferta de emprego

About the Role

Our client, a rapidly growing pharmaceutical company, is seeking a highly skilled Chemical Engineer to join their process development team in Klerksdorp, North West. This role is crucial for the development, optimization, and scale-up of chemical synthesis processes for active pharmaceutical ingredients (APIs) and intermediates. You will work in a Good Manufacturing Practice (GMP) environment, ensuring the production of high-quality pharmaceuticals. The position requires a strong understanding of organic chemistry, reaction engineering, and process scale-up principles. This is an excellent opportunity for a detail-oriented engineer to contribute to life-saving medicines in a dynamic and innovative setting. You will be an integral part of the product lifecycle, from early-stage development to commercial manufacturing support.

Key Responsibilities

• Develop and optimize chemical synthesis routes for APIs and intermediates.
• Design and conduct laboratory experiments for process characterization and validation.
• Perform process scale-up from bench to pilot plant and commercial manufacturing.
• Utilize process modeling and simulation tools to enhance understanding and efficiency.
• Ensure all process development activities comply with GMP, regulatory, and safety standards.
• Collaborate with R&D chemists, analytical scientists, and manufacturing personnel.
• Troubleshoot process deviations and implement corrective and preventive actions (CAPAs).
• Author process development reports, validation protocols, and regulatory submission documentation.

Requirements

• Bachelor's or Master's degree in Chemical Engineering.
• Minimum of 6 years of experience in pharmaceutical process development or fine chemical manufacturing.
• Strong background in organic chemistry and reaction engineering.
• Experience with process scale-up, technology transfer, and GMP environments.
• Proficiency in process simulation software and statistical analysis (DOE).
• Knowledge of regulatory guidelines (e.g., FDA, EMA) for pharmaceutical manufacturing.
• Excellent analytical, problem-solving, and documentation skills.
• Strong interpersonal skills and ability to work effectively in cross-functional teams.

Benefits

• Our client offers a competitive salary, comprehensive health insurance, retirement planning, and performance-based incentives.
• They provide significant opportunities for professional growth, including training in advanced pharmaceutical technologies and participation in international conferences.
• You will work in a state-of-the-art facility with a team dedicated to advancing healthcare through innovative pharmaceutical development.