Biologics Process Development Scientist — Hybrid & Growth

Placements24; Stellenbosch; Híbrido; ZAR 1.200.000 - 2.000.000; Tempo integral

Benefícios oferecidos por esta vaga

Hybrid work model

Competitive salary and bonus potential

Health, dental, vision benefits

Retirement plan

Paid time off

Resumo da vaga

Placements24 is seeking a Biologics Process Development Scientist to join a leadership-driven biopharma R&D team in Stellenbosch. The role focuses on developing and optimizing upstream and downstream processes for novel biologics, with an emphasis on scale-up and technology transfer to manufacturing.

You will design experiments, evaluate process parameters, and ensure product quality and consistency while adhering to cgMP standards and regulatory requirements.

Qualificações

• Ph.D. or Master’s degree in Chemical Engineering, Biochemical Engineering, Biotechnology, or a related field.
• 4–7 years in biopharmaceutical process development.
• Hands-on cell culture (upstream) and purification for biologics.
• Experience with process scale-up, optimization, and tech transfer.

Responsabilidades

• Develop and optimize upstream and downstream processes for recombinant proteins and monoclonal antibodies.
• Design and execute experiments to evaluate process parameters and impact on yield, quality, and consistency.
• Scale-up lab processes to pilot and manufacturing scale with technology transfer.
• Characterize process intermediates and final drug substance using analytical techniques.
• Troubleshoot process issues and implement corrective actions.
• Contribute to process validation studies and regulatory submissions.
• Prepare technical reports and development summaries.
• Collaborate with analytical development, manufacturing, QA, and regulatory teams.
• Stay current with emerging bioprocess technologies and cGMP practices.

Conhecimentos

Bioprocess engineering

Cell culture

Purification techniques

Tech transfer

Analytical thinking

Problem solving

Formação

Ph.D. or Master’s in Chemical/Biochemical Engineering or Biotechnology

Ferramentas

HPLC

ELISA

SDS-PAGE

Descrição da vaga

Placements24 is seeking a Biologics Process Development Scientist to join a leadership-driven biopharma R&D team in Stellenbosch. The role focuses on developing and optimizing upstream and downstream processes for novel biologics, with an emphasis on scale-up and technology transfer to manufacturing.

You will design experiments, evaluate process parameters, and ensure product quality and consistency while adhering to cgMP standards and regulatory requirements.