VP Translational Medicine & Biomarker Strategy

Automatic Data Processing, Inc.; Watertown (MA); On-site; USD 230,000 - 330,000; Full time

Job summary

Seismic Therapeutic in Watertown, MA seeks a Senior Director/VP of Translational Medicine to own translational and biomarker strategy across our clinical and preclinical immunology programs. Reporting to the CMO, you will connect mechanism to patients from target biology through first‑in‑human studies and dose selection.

This senior role combines strategic leadership with hands‑on analysis of multimodal data and represents translational science with health authorities, academic experts, and

Qualifications

• PhD or MD/PhD in immunology or related field.
• Broad drug development experience with portfolio‑level scope.
• Experience designing biomarker and PK/PD strategies for early clinical studies.
• Proven ability to engage with disease experts and health authorities.

Responsibilities

• Define translational medicine and biomarker strategies for Seismic programs.
• Shape preclinical pharmacology and human ex vivo models to support IND enabling studies.
• Lead biomarker content of regulatory documents and health authority interactions.
• Direct multimodal data generation and ensure assay fit-for-purpose qualification.
• Build networks with experts and collaborators for access to patient samples.

Skills

Immunology

Drug development

Biomarkers

Translational medicine

Clinical development

Regulatory interactions

IND/CTA filings

Data interpretation

Education

PhD or MD/PhD in immunology

Tools

Flow cytometry

Mass cytometry

Transcriptomics

Proteomics

Bioinformatics

Job description

Seismic Therapeutic in Watertown, MA seeks a Senior Director/VP of Translational Medicine to own translational and biomarker strategy across our clinical and preclinical immunology programs. Reporting to the CMO, you will connect mechanism to patients from target biology through first‑in‑human studies and dose selection.

This senior role combines strategic leadership with hands‑on analysis of multimodal data and represents translational science with health authorities, academic experts, and