VP, Oncology Clinical Development & Translational AI

Xaira Therapeutics; South San Francisco (CA); On-site; USD 350,000 - 407,000; Full time

Benefits offered by this job

Equity

Bonus

Health benefits

Job summary

Xaira Therapeutics, Inc. invites an experienced Vice President, Oncology to shape the clinical development of its cancer portfolio. You will lead IND/CTA strategy, first‑in‑human design, and translational biomarker programs, steering translational science and AI-enabled insights across the development continuum.

The role requires building the clinical development function, establishing governance, and partnering with external experts to progress programs toward registrational outcomes.

Qualifications

• MD/MD‑PhD required with residency and board certification in oncology strongly preferred.
• Minimum 12 years in clinical development with 5+ years in leadership.
• Experience leading IND/CTA strategy and one oncology program through Phase 1/2/3.
• Biomarker-driven development and AI in oncology applications an advantage.

Responsibilities

• Define and own integrated clinical development plans for priority oncology programs.
• Lead IND/CTA submissions and first‑in‑human study design and execution.
• Define translational and biomarker strategies and patient selection approaches.
• Oversee late‑stage transition, registry goals, and regulatory alignment.
• Build and lead the clinical development team and external partnerships.
• Collaborate with AI, translational science, and regulatory teams to inform decisions.

Skills

Leadership

Oncology expertise

Regulatory strategy

Clinical development leadership

AI/data analytics in oncology

Education

MD or MD/PhD

Job description

Xaira Therapeutics, Inc. invites an experienced Vice President, Oncology to shape the clinical development of its cancer portfolio. You will lead IND/CTA strategy, first‑in‑human design, and translational biomarker programs, steering translational science and AI-enabled insights across the development continuum.

The role requires building the clinical development function, establishing governance, and partnering with external experts to progress programs toward registrational outcomes.