Director, AI-Driven Oncology Portfolio

Pfizer Inc; Rheba (CA); Hybrid; USD 177,000 - 294,000; Full time

Benefits offered by this job

401(k) plan with Pfizer Matching and a

paid vacation

holiday and personal days

health benefits to include medical, Rx

Job summary

Pfizer is seeking an AI-enabled Portfolio Lead in Oncology Research to integrate AI strategies across our pipeline, bridging advanced analytics with oncology expertise to guide portfolio decisions.

Reporting to the Head of Portfolio Strategy and Program Management, you will analyze projects using predictive models and scenario simulations, inform governance discussions, and drive data-driven prioritization and resource allocation across discovery through preclinical programs.

Qualifications

• PhD in a relevant scientific field with 5+ years using AI in drug discovery.
• Experience with AI/ML teams or tools in R&D processes.
• Ability to translate complex data into decisions and influence stakeholders.
• Strong knowledge of Oncology R&D workflows and data-driven decision making.
• 10+ years in pharma/biotech R&D in strategic roles.
• Understanding across modalities (small molecules, biologics, ADCs).

Responsibilities

• Analyze oncology portfolio from discovery to preclinical using AI/ML to assess programs.
• Develop data-driven portfolio strategies for senior leaders.
• Integrate AI-derived insights into governance discussions.
• Collaborate across discovery, translational, clinical, and business teams.
• Prepare AI-enabled project strategy recommendations for governance meetings.

Skills

AI/ML in R&D

Portfolio analysis

Data visualization

Stakeholder communication

Cross-functional collaboration

Education

PhD in a relevant scientific field

Tools

Predictive modeling

Knowledge graphs

Dashboard visualization

Job description

Pfizer is seeking an AI-enabled Portfolio Lead in Oncology Research to integrate AI strategies across our pipeline, bridging advanced analytics with oncology expertise to guide portfolio decisions.

Reporting to the Head of Portfolio Strategy and Program Management, you will analyze projects using predictive models and scenario simulations, inform governance discussions, and drive data-driven prioritization and resource allocation across discovery through preclinical programs.