VP, Clinical Operations – Oncology Biotech

Planet Pharma; Philadelphia (Philadelphia County); On-site; USD 300,000 - 420,000; Full time

Job summary

Planet Pharma in Philadelphia seeks a hands-on VP/Head of Clinical Operations to provide strategic and operational leadership across multiple early-phase oncology programs.

You will oversee CROs and vendors, manage timelines and budgets, build scalable processes, and mentor a lean clinical operations team in a fast-paced biotech environment. This role offers potential for contract-to-permanent transition and requires collaboration with Regulatory Affairs, Data Management, and Medical Affairs.

Qualifications

• Bachelor’s degree in life sciences or related field; advanced degree preferred.
• Significant leadership experience in biotech/pharma clinical operations.
• Proven track record managing early-phase oncology trials.

Responsibilities

• Provide strategic oversight and leadership for multiple early-phase oncology clinical trials (Phase 1, Phase 2a, and Phase 2b).
• Lead and direct all clinical operations activities to ensure successful study execution, quality, timelines, and budget adherence.
• Manage and oversee CROs, vendors, and external partners to ensure performance, compliance, and operational excellence.
• Develop and maintain clinical study plans, timelines, risk mitigation strategies, and operational metrics.
• Collaborate cross-functionally with Clinical Development, Regulatory Affairs, Data Management, Biometrics, Medical Affairs, and other key stakeholders.
• Drive operational readiness for study start-up, enrollment, data collection, and closeout activities.

Skills

Leadership

Clinical operations

Budget management

CRO oversight

GCP/ICH

Cross-functional collaboration

Education

Bachelor’s degree in Life Sciences

Advanced degree

Job description

Planet Pharma in Philadelphia seeks a hands-on VP/Head of Clinical Operations to provide strategic and operational leadership across multiple early-phase oncology programs.

You will oversee CROs and vendors, manage timelines and budgets, build scalable processes, and mentor a lean clinical operations team in a fast-paced biotech environment. This role offers potential for contract-to-permanent transition and requires collaboration with Regulatory Affairs, Data Management, and Medical Affairs.