Executive Director Clinical Operations

Barrington James; United States; On-site; USD 210,000 - 320,000; Full time

Job summary

Barrington James is seeking an AVP, Clinical Operations for a confidential search focused on Global Oncology (Commercial-Stage, NASDAQ-listed). This leadership role requires overseeing late-stage oncology trials, interacting with Regulatory, Development, Biostatistics, and Commercial teams, and managing CRO relationships across the US, EU, and Asia-Pacific.

The successful candidate will have 10+ years in clinical operations, with direct experience in global registrational (Phase III) oncology

Qualifications

• 10+ years in clinical operations (Pharma/Biotech/CRO)
• Experience leading global registrational (Phase III) oncology trials
• Strong cross-functional leadership and vendor oversight
• Experience navigating FDA/EMA regulatory environments
• Oncology experience preferred

Responsibilities

• Provide strategic and operational leadership across global registrational oncology trials
• Partner with Clinical Development, Regulatory, Biostatistics and Commercial teams
• Oversee CRO/vendor management across US, EU, and Asia-Pacific sites
• Drive trial timelines, budget, and risk management for late-stage oncology programs
• Contribute to clinical operations strategy as the company scales globally

Skills

Clinical operations leadership

Global registrational trials

Vendor/CRO oversight

Cross-functional leadership

Regulatory knowledge (FDA/EMA)

Education

Advanced life sciences degree

Tools

CTMS

Job description

AVP, Clinical Operations Confidential Search | Global Oncology (Commercial-Stage, NASDAQ-listed) EAST COAST ONLY

The Role

• Provide strategic and operational leadership across a portfolio of global registrational trials
• Partner cross-functionally with Clinical Development, Regulatory, Biostatistics, and Commercial teams
• Oversee CRO relationships and vendor management across US, EU, and Asia-Pacific sites
• Drive trial timelines, budget, and risk management for late-stage oncology programs
• Contribute to clinical operations strategy as the company scales from single-market commercial success into global regulatory execution

What They're Looking For

• 10+ years of clinical operations experience, including senior/leadership roles within Pharma, Biotech, or CRO settings
• Direct experience managing global registrational (Phase III) oncology trials
• Strong track record of cross-functional leadership and vendor/CRO oversight
• Experience operating across US and international regulatory environments (FDA/EMA)
• Prior oncology therapeutic area experience strongly preferred