US Commercial Enablement Director: Strategy, CRM & Launch

BioSpace; Waltham (MA); Hybrid; USD 188,000 - 235,000; Full time

Job summary

Dyne Therapeutics, based in Waltham, MA, seeks a Director of US Commercial Enablement to drive strategic enablement initiatives and build tools, processes, and capabilities for growth and launch readiness. You will optimize field infrastructure, incentive plans, CRM, and analytics to support commercial execution.

The role requires 12+ years in biotech or life sciences with launch experience, strong leadership, analytical skills, and the ability to collaborate across teams.

Qualifications

• 12+ years of experience in biotech, pharmaceutical, or life sciences industry, including field sales, sales leadership, field operations, or consulting experience supporting commercial organizations.
• Demonstrated experience supporting or leading launch readiness, ideally in rare disease, neuromuscular, neurodegenerative, or neurodevelopmental therapies.
• Strong leadership and project management experience, including managing vendors and scaling commercial infrastructure.
• Strategic mindset with ability to execute and deliver results.
• Excellent written and verbal communication skills, including ability to present to senior leadership.
• Demonstrated ability to collaborate effectively across cross-functional stakeholders.

Responsibilities

• Leads planning, design, and administration of incentive compensation and bonus programs across commercial, medical, and patient services teams
• Develops plan design models, manages payouts, and delivers monthly and quarterly reporting
• Maintains plan documentation, tracking systems, and performance monitoring processes
• Conducts regular performance reviews with stakeholders to optimize program effectiveness
• Partners with field teams to build account planning tools
• Leads recognition programs, including Circle of Excellence and associated planning
• Serves as commercial business owner for CRM platforms (e.g., Veeva)
• Owns business intelligence reporting tools and ensures data accuracy through quality control processes
• Supports reporting platforms across market access and patient services
• Optimizes field enablement tools and materials to improve productivity and effectiveness

Skills

Leadership

Project management

Vendor management

Strategic thinking

Analytical skills

Communication skills

Cross-functional collaboration

Education

Bachelor’s degree; advanced degree preferred

Tools

CRM platforms (Veeva)

BI tools

Snowflake

Boomi

Job description

Dyne Therapeutics, based in Waltham, MA, seeks a Director of US Commercial Enablement to drive strategic enablement initiatives and build tools, processes, and capabilities for growth and launch readiness. You will optimize field infrastructure, incentive plans, CRM, and analytics to support commercial execution.

The role requires 12+ years in biotech or life sciences with launch experience, strong leadership, analytical skills, and the ability to collaborate across teams.