Upstream Cell Culture Scientist — Biologics Development

Sanofi; Framingham (MA); On-site; USD 85,000 - 120,000; Full time

Job summary

Sanofi is seeking an Associate Scientist in Cell Culture Development to join the Framingham, MA team. The role focuses on upstream development, maintaining bioreactor automation, and collaborating with the Cell Culture Development Group to advance robust, scalable processes for diverse biologics pipelines.

The candidate will execute experiments, prepare protocols, troubleshoot challenges, and contribute to team meetings, with emphasis on sterile technique and data integrity in a fast-paced

Qualifications

• Minimum of 3 months of experience or equivalent exposure in a cell culture or biological laboratory setting (coursework, undergraduate research, or internship experience will also be considered).
• Working knowledge of aseptic technique.

Responsibilities

• Execute upstream process development experiments under general supervision; independently execute simple experiments and support complex experiments.
• Execute cell separation and harvest experiments evaluating centrifugation and depth filtration strategies.
• Maintain laboratory bioreactor automation, including routine setup, calibration and troubleshooting of common issues.
• Participate in upstream and cell line development team meetings to support team goals.
• Prepare experimental protocols, perform troubleshooting of common cell culture challenges (e.g. contamination), and author templated technical reports with supervision.
• Maintain high-quality deliverables, open communication, and a collaborative working environment.
• Develop an understanding of the basic technical principles underlying cell culture theory and experimentation (e.g. sterile technique, mass transfer).
• Contribute to upstream, cell line development or technology development teams that develop and implement industry leading cell culture production technologies and platforms.
• Suggest improvements in the execution of standard cell culture experiments and participate in initiatives to improve upstream process development approaches.
• Adhere to all relevant HSE procedures and guidelines, lab guidance documents (LOPs, SOPs) and safety training, including data integrity and documentation practices.
• Present experimental results at lab meetings or within the upstream team.

Skills

Cell culture experience

Aseptic technique

Communication

Education

Bachelor's degree in Biology or related field

Job description

Sanofi is seeking an Associate Scientist in Cell Culture Development to join the Framingham, MA team. The role focuses on upstream development, maintaining bioreactor automation, and collaborating with the Cell Culture Development Group to advance robust, scalable processes for diverse biologics pipelines.

The candidate will execute experiments, prepare protocols, troubleshoot challenges, and contribute to team meetings, with emphasis on sterile technique and data integrity in a fast-paced