Translational T1D Research Leader (Physician-Scientist)

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 197,000 - 296,000; Full time

Benefits offered by this job

Annual bonus

Annual equity awards

Generous paid time off

Job summary

Vertex Pharmaceuticals LLC seeks an innovative physician-scientist to lead translational research and product strategy for the Type 1 Diabetes Research Group in Boston. This role bridges clinical expertise with translational science to advance SC-islet therapies from discovery through translational development.

The candidate should have 10+ years in academic medicine or biotech translational research, with strong diabetes and cell therapy experience, and a product-development mindset.

Qualifications

• MD or MD/PhD with 10+ years in academic medicine, translational research, biotechnology, pharmaceutical R&D, or related settings.
• Expertise in drug development, translational science, and disease biology.
• Experience in cell therapy, stem cell biology, regenerative medicine, endocrinology, immunology, or related fields.
• Strong track record in diabetes, cell therapy, translational therapeutics, stem cell biology, or related disciplines.

Responsibilities

• Provide disease and mechanistic insight to support product strategy, hypothesis generation, and candidate optimization.
• Serve as a physician-scientist leader for translational strategy in partnership with research, development, manufacturing, and clinical teams.
• Design and guide in vitro and in vivo studies aiming for clinical outcomes.
• Lead cross-functional projects, setting goals, priorities, timelines, budgets, and decision points.
• Integrate biological, translational, engineering, manufacturing, and clinical considerations to drive portfolio decisions and product advancement.
• Define and guide development of predictive assays, biomarkers, and translational strategies supporting product advancement.
• Interpret complex datasets and convert findings into clear program recommendations.
• Build and maintain a strong, collaborative, high-performing research culture.

Skills

Diabetes expertise

Translational medicine

Cell therapy knowledge

Strategic product development

Education

MD or MD/PhD

Job description

Vertex Pharmaceuticals LLC seeks an innovative physician-scientist to lead translational research and product strategy for the Type 1 Diabetes Research Group in Boston. This role bridges clinical expertise with translational science to advance SC-islet therapies from discovery through translational development.

The candidate should have 10+ years in academic medicine or biotech translational research, with strong diabetes and cell therapy experience, and a product-development mindset.