Translational Diabetes Physician-Scientist Leader

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 197,000 - 296,000; Full time

Job summary

Vertex Pharmaceuticals Incorporated is seeking an innovative physician-scientist to lead translational research and product strategy within the Type 1 Diabetes Research Group. The role bridges clinical expertise with translational science to advance SC-islet therapies from discovery through development.

The candidate will integrate disease biology, stem cell biology, bioengineering, manufacturing, and clinical considerations to guide portfolio decisions and future clinical development.

Qualifications

• MD and/or MD/PhD in a relevant discipline with 10+ years in academic medicine, translational research, biotechnology, pharmaceutical R&D, or related settings.
• Expertise in drug development, translational science, and disease biology.
• Experience in cell therapy, stem cell biology, regenerative medicine, endocrinology, immunology, or related fields.
• Strong track record in diabetes, cell therapy, translational therapeutics, stem cell biology, or related disciplines.

Responsibilities

• Provide disease and mechanistic insight to support product strategy, hypothesis generation, and candidate optimization.
• Serve as a physician-scientist leader for translational strategy in partnership with research, development, manufacturing, and clinical teams.
• Design and guide in vitro and in vivo studies aiming for clinical outcomes.
• Lead cross-functional projects, setting goals, priorities, timelines, budgets, and decision points.
• Integrate biological, translational, engineering, manufacturing, and clinical considerations to drive portfolio decisions and product advancement.
• Define and guide development of predictive assays, biomarkers, and translational strategies supporting product advancement.
• Interpret complex datasets and convert findings into clear program recommendations.
• Build and maintain a strong, collaborative, high-performing research culture.

Skills

Translational medicine

Diabetes expertise

Cross-functional leadership

Drug development

Product strategy

Education

MD

MD/PhD

Job description

Vertex Pharmaceuticals Incorporated is seeking an innovative physician-scientist to lead translational research and product strategy within the Type 1 Diabetes Research Group. The role bridges clinical expertise with translational science to advance SC-islet therapies from discovery through development.

The candidate will integrate disease biology, stem cell biology, bioengineering, manufacturing, and clinical considerations to guide portfolio decisions and future clinical development.