Clinical Director, Translational Neuroscience

Merck

Boston (MA)

Hybrid

USD 256,000 - 403,000

Full time

3 days ago

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Job summary

Merck seeks a Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development within the Neuroscience Therapeutic Area, based in the US. This physician-scientist will lead cross-functional teams to advance neurologic and psychiatric programs from preclinical insights to early clinical trials.

The role emphasizes leadership, biomarker development, and collaboration with discovery, pharmacology, regulatory affairs, and global clinical operations to deliver innovative

Qualifications

Doctoral degree (MD or MD/PhD) required.
Board certification or eligibility in Neurology or Psychiatry preferred.
Strong publications record and ability to work across therapeutics.

Responsibilities

Provide clinical expertise for target identification and validation.
Collaborate with cross-functional teams to advance therapeutics into clinical development.
Lead early development strategies for Phase 1–2 with PK/PD and biomarker work.
Develop clinical pharmacology studies across all phases.
Support regulatory filings with documentation and presentations.
Engage in biomarker strategy development and validation.

Skills

Biomedical Research

Clinical Development

Clinical Medicine

Clinical Research

Clinical Trial Planning

Cross-Functional Teamwork

Neuroscience Research

Neurologic Disorders

Translational Medicine

Translational Research

Education

Doctoral degree (MD or MD/PhD)

Job description

The role emphasizes leadership, biomarker development, and collaboration with discovery, pharmacology, regulatory affairs, and global clinical operations to deliver innovative

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