Toxicologist

ITG Brands; North Carolina; Hybrid; USD 138,000 - 185,000; Full time

Benefits offered by this job

Medical/dental/vision insurance

401(k) with company match

Paid holidays

Hybrid workplace

Education assistance

Employee recognition

Employee referral bonus

Summer hours

Casual dress

Job summary

ITG Brands in the United States seeks a senior toxicologist to lead toxicology strategies for PMTA and other regulatory submissions, aligning with FDA expectations and consumer safety.

You will manage human health risk assessments, author toxicology sections of submissions, and oversee studies (in vitro and computational) in collaboration with CROs. The role offers a competitive benefits package and a hybrid work arrangement.

Qualifications

• Ph.D. or Master’s in Toxicology, Pharmacology, or a related life science field.
• 7–10 years in human health risk assessment in FDA-regulated environments (tobacco/pharma/consumer products).
• Diplomate of the American Board of Toxicology (DABT) strongly preferred; willingness to obtain if not certified.
• Knowledge of FDA regulatory pathways (PMTA/SE submissions) and ability to lead regulatory strategy development.
• Experience with in vitro and computational toxicology and data interpretation.

Responsibilities

• Lead development of toxicology strategies for PMTA and regulatory submissions.
• Oversee human health risk assessments for ingredients, materials, and finished products with focus on regulatory compliance and safety.
• Author and manage toxicology sections of regulatory submissions with scientific rigor and clarity.
• Design, execute, and interpret toxicology studies (in vitro and computational), often with CRO collaboration.
• Evaluate and interpret toxicological data to support regulatory positions.
• Represent the company in FDA meetings, scientific conferences, and industry forums.
• Collaborate with product development, regulatory, and legal teams to integrate toxicology data into regulatory strategies.
• Monitor evolving regulatory requirements and methodologies to ensure proactive compliance and innovation.

Skills

Toxicology

Regulatory strategy

Communication

Data analysis

Computational toxicology

Education

Ph.D. or Master’s in Toxicology/Pharmacology or related life science

Tools

Microsoft Office

Scientific data analysis tools

Job description

Who We Are

ITG Brands is the third-largest tobacco company in the USA with offerings of some of the most well-known cigarette, cigar, and e-vapor brands. As a member of the globally recognized Imperial Brands PLC family, we are a forward-thinking partner with operational integrity.

Who We Are

ITG Brands is the third-largest tobacco company in the USA with offerings of some of the most well-known cigarette, cigar, and e-vapor brands. As a member of the globally recognized Imperial Brands PLC family, we are a forward-thinking partner with operational integrity. ITG Brands is committed to putting consumers at the center of what we do, while creating an innovative workplace where inclusion, creativity, and bold thinking drive progress. This empowers us to bring our true selves to work, to collaborate more effectively through showing our passion and being confident to bring new ideas to the table. We are not afraid to seize opportunities and make things happen – both individually and collaboratively. We strive to exceed expectations by seeing things differently and doing things differently. This truly is a place where we all share a challenger mindset which drives our success.

What You Will Do

• JOB SUMMARY

• WHAT YOU WILL DO

Key Responsibilities

• Lead the development of toxicology strategies for PMTA and other regulatory submissions, ensuring alignment with FDA expectations and public health standards.
• Oversee and conduct human health risk assessments for ingredients, materials, and finished products, with a focus on regulatory compliance and consumer safety.
• Author and manage the toxicology sections of regulatory submissions, ensuring scientific rigor, clarity, and completeness
• Direct the design, execution, and interpretation of toxicology studies, including in vitro and computational toxicology, often in collaboration with CROs.
• Evaluate and interpret toxicological data, including studies from scientific literature, to determine potential health impacts and support the development of scientific positions.
• Serve as a regulatory-facing subject matter expert, representing the company in FDA meetings, scientific conferences, and industry forums.
• Collaborate cross-functionally with product development, regulatory affairs, and legal teams to integrate toxicology data into broader regulatory strategies.
• Monitor evolving regulatory requirements, toxicological methodologies, and risk assessment frameworks to ensure proactive compliance and innovation.

Qualifications

• Education: Ph.D. or Master’s in Toxicology, Pharmacology, or a related life science field.
• Experience: Minimum of 7–10 years in human health risk assessment, with direct experience in FDA-regulated environments (preferably tobacco, pharmaceutical, or consumer products).
• Certification: Diplomate of the American Board of Toxicology (DABT) strongly preferred; candidates should be willing to obtain if not already certified.
• Certifications: Certifications such as Diplomate of the American Board of Toxicology (DABT). Candidates who do not currently hold these certifications should be willing to obtain them.
• In-depth knowledge of FDA regulatory pathways, especially PMTA and SE submissions.
• Proven ability to lead toxicological evaluations and regulatory strategy development.
• Experience with advanced toxicological testing methods, computational modeling, and statistical analysis.
• Strong communication skills, with the ability to present complex scientific concepts to regulatory bodies and non-scientific stakeholders.
• Proficiency in Microsoft Office and scientific data analysis tools.

What We Offer

• Competitive benefits package that includes medical/dental/vision/life insurance/disability plans
• Dollar for dollar 401k match up to 6% and 5% annual company contribution
• 15 Company-paid holidays
• Generous paid time off
• Employee recognition and discount programs
• Education assistance
• Employee referral bonus program
• Hybrid workplace – remote / in office
• Summer hours
• Casual dress policy Monday through Friday

Annual Base Salary Range: $138417.00 - $184555.00

Final compensation will be determined based on experience, qualifications, and internal equity. This role may also be eligible for annual bonus or incentive compensation.

Applicant Information

This job description describes the essential functions of the job at the time the job description was created, but it is not an exhaustive list of tasks, duties and responsibilities. In addition, the position may evolve or change over time and such changes may not be reflected in the job description until it is next updated.

Everyone Belongs

ITG Brands and ITG Cigars provides equal employment opportunities.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. If you have a concern about discrimination in the application or hiring process or you need an accommodation based on religion, disability or pregnancy in the application or hiring process, please contact us at [e-mail] .