Toxicologist

ITG Brands, LLC; Greensboro (NC); Hybrid; USD 138,000 - 185,000; Full time

Benefits offered by this job

Medical/dental/vision/life insurance

401k match up to 6% and 5% company 25

15 Company-paid holidays

Generous paid time off

Employee recognition and discount 프로그램

Education assistance

Employee referral bonus program

Hybrid workplace – remote / in office

Summer hours

Casual dress policy Monday through Fri

Job summary

ITG Brands, LLC in Greensboro, NC is seeking a Senior Toxicologist to shape regulatory strategy for PMTA submissions and to manage toxicology programs for tobacco products, ensuring robust data supports marketing approvals.

The role leads toxicology strategy development, oversees risk assessments, and authors regulatory submissions, coordinating with CROs and cross-functional teams to ensure compliant, innovative approaches.

Qualifications

• Ph.D. or Master’s in Toxicology, Pharmacology, or related life science field.
• Minimum of 7–10 years in human health risk assessment in FDA-regulated environments (preferably tobacco, pharmaceutical, or consumer products).
• Diplomate of the American Board of Toxicology (DABT) strongly preferred; willing to obtain if not certified.

Responsibilities

• Lead the development of toxicology strategies for PMTA and other regulatory submissions.
• Oversee and conduct human health risk assessments for ingredients, materials, and finished products.
• Author and manage the toxicology sections of regulatory submissions.
• Direct the design, execution, and interpretation of toxicology studies, including in vitro and computational toxicology.
• Evaluate and interpret toxicological data to determine potential health impacts and support scientific positions.
• Serve as regulatory-facing SME in FDA meetings, conferences, and industry forums.
• Collaborate with product development, regulatory affairs, and legal teams to integrate toxicology data.
• Monitor evolving regulatory requirements and methodologies to ensure compliance and innovation.

Skills

Regulatory toxicology

Toxicology study design

Regulatory submissions

Data analysis

Regulator communications

Education

Ph.D. in Toxicology

Master’s in Toxicology

Tools

Microsoft Office

Statistical analysis tools

Computational toxicology tools

Job description

ITG Brands is the third-largest tobacco company in the USA with offerings of some of the most well-known cigarette, cigar, and e-vapor brands. As a member of the globally recognized Imperial Brands PLC family, we are a forward-thinking partner with operational integrity.

ITG Brands is committed to putting consumers at the center of what we do, while creating an innovative workplace where inclusion, creativity, and bold thinking drive progress. This empowers us to bring our true selves to work, to collaborate more effectively through showing our passion and being confident to bring new ideas to the table.

We are not afraid to seize opportunities and make things happen – both individually and collaboratively. We strive to exceed expectations by seeing things differently and doing things differently. This truly is a place where we all share a challenger mindset which drives our success.

What You Will Do

- JOB SUMMARY

The Senior Toxicologist plays a pivotal role in shaping regulatory strategy and scientific direction for tobacco product submissions, including Premarket Tobacco Product Applications (PMTAs). They manage the toxicological risk assessment programs for both conventional and reduced-risk tobacco products, ensuring the data is scientifically robust and supports the product's marketing approval.

- WHAT YOU WILL DO

Key Responsibilities:

Lead the development of toxicology strategies for PMTA and other regulatory submissions, ensuring alignment with FDA expectations and public health standards.

Oversee and conduct human health risk assessments for ingredients, materials, and finished products, with a focus on regulatory compliance and consumer safety.

Author and manage the toxicology sections of regulatory submissions, ensuring scientific rigor, clarity, and completeness

Direct the design, execution, and interpretation of toxicology studies, including in vitro and computational toxicology, often in collaboration with CROs.

Evaluate and interpret toxicological data, including studies from scientific literature, to determine potential health impacts and support the development of scientific positions.

Serve as a regulatory-facing subject matter expert, representing the company in FDA meetings, scientific conferences, and industry forums.

Collaborate cross-functionally with product development, regulatory affairs, and legal teams to integrate toxicology data into broader regulatory strategies.

Monitor evolving regulatory requirements, toxicological methodologies, and risk assessment frameworks to ensure proactive compliance and innovation.

Qualifications

- REQUIRED MINIMUM QUALIFICATIONS:

Education: Ph.D. or Master’s in Toxicology, Pharmacology, or a related life science field.

Experience: Minimum of 7–10 years in human health risk assessment, with direct experience in FDA-regulated environments (preferably tobacco, pharmaceutical, or consumer products).

Certification: Diplomate of the American Board of Toxicology (DABT) strongly preferred; candidates should be willing to obtain if not already certified.

Certifications: Certifications such as Diplomate of the American Board of Toxicology (DABT). Candidates who do not currently hold these certifications should be willing to obtain them.

Expertise:

In-depth knowledge of FDA regulatory pathways, especially PMTA and SE submissions.

Proven ability to lead toxicological evaluations and regulatory strategy development.

Experience with advanced toxicological testing methods, computational modeling, and statistical analysis.

Strong communication skills, with the ability to present complex scientific concepts to regulatory bodies and non-scientific stakeholders.

Proficiency in Microsoft Office and scientific data analysis tools.

What We Offer

• Competitive benefits package that includes medical/dental/vision/life insurance/disability plans
• Dollar for dollar 401k match up to 6% and 5% annual company contribution
• 15 Company-paid holidays
• Generous paid time off
• Employee recognition and discount programs
• Education assistance
• Employee referral bonus program
• Hybrid workplace – remote / in office
• Summer hours
• Casual dress policy Monday through Friday

Annual Base Salary Range: $138417.00 - $184555.00

Final compensation will be determined based on experience, qualifications, and internal equity. This role may also be eligible for annual bonus or incentive compensation.

This job description describes the essential functions of the job at the time the job description was created, but it is not an exhaustive list of tasks, duties and responsibilities. In addition, the position may evolve or change over time and such changes may not be reflected in the job description until it is next updated.

Everyone Belongs

ITG Brands and ITG Cigars provides equal employment opportunities.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. If you have a concern about discrimination in the application or hiring process or you need an accommodation based on religion, disability or pregnancy in the application or hiring process, please contact us at [e-mail] .

SHARE THIS JOB

The posting for the position for which you are applying highlights key aspects of the position only. It is not a complete description of the position.

All candidates must consent to an independent investigation of their background, references, past employment, education, criminal record, and drug screening. Results of such background checks will be reviewed on a case-by-case basis, giving consideration to the nature of the information reported and its relevance to the specific job being sought before a decision is made using this information.

ITG Brands and ITG Cigars provides equal employment opportunities. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. If you have a concern about discrimination in the application or hiring process or you need an accommodation based on religion, disability or pregnancy in the application or hiring process, please contact us at [e-mail] .

We collect personal information from you in connection with your application for employment with ITG Brands or ITG Cigars. For more information, please see our Privacy Policy . If you are a job applicant from California, additional information can be found on our California Applicant Privacy Notice . If you have questions, contact us at [e-mail] .