Temp - Sr. Scientist - Antibody Engineering

Regeneron Pharmaceuticals, Inc.; Village of Tarrytown (NY); Presencial; USD 150.000 - 190.000; Jornada completa

Descripción de la vacante

Regeneron Pharmaceuticals, Inc. is seeking a Sr. Scientist in Antibody Engineering to design, produce, and evaluate engineered antibodies. The role focuses on bi- and multi-specific antibody concepts and involves closely coordinating with cross-functional teams.

You will work with mammalian expression systems, perform cell-based assays, and present data at group meetings. A PhD in biochemistry or cell biology is required, with a strong publication and collaboration track record preferred.

Formación

• PhD in biochemistry, cell biology or related field.
• Proven track record in antibody/protein engineering.
• Experience with mammalian expression systems.

Responsabilidades

• Design bi- and multi-specific antibodies.
• Produce engineered antibody panel via mammalian expression and purification.
• Perform in vitro cell-handling experiments including transfection and viral transduction.
• Run and troubleshoot assays such as ELISA, FACS, Western blot, and qPCR.
• Collaborate with TFA groups to align on designs and cross-department goals.
• Analyze and present data at meetings and maintain ELN records.

Conocimientos

Cell-based assays

FACS

DNA cloning

Protein production

Purification

Transfection

RNA analysis

Protein analysis

Immunostaining

Presentation skills

Educación

PhD in Biochemistry / Cell Biology

Descripción del empleo

Temp - Sr. Scientist - Antibody Engineering -

R51829

Position Description

We are seeking a highly motivated Sr. Scientist with expertise in antibody and protein engineering, who will help development of bi- and multi-specific antibodies in designing, producing, and evaluating engineered antibodies.

Roles Responsibilities

• Applying molecular biology expertise to design new bi- and multi-specific antibody
• Producing engineered antibodies panel through mammalian expression and purification
• Performing in vitro cell-handling experiments, including cell transfection, and cell transduction with viral vectors
• Running and troubleshooting assays, including ELISA, FACS, Western blotting, qPCR
• Collaborating with TFA groups to align on fit-for-purpose engineered antibody designs and coordinating cross-departmental research objectives
• Analyzing and presenting data at group and departmental meetings, and maintaining records in electronic lab notebooks

Skills

• You are result-driven and fast-learning.
• You have a strong background in with cell-based assays and FACS
• You have experiences molecular biology with DNA cloning, protein production and purification
• You have strong organizational, time-management, and presentation skills
• You enjoy working in a fast-paced, innovative and cross-functional team
• A strong record of innovation and research accomplishments in the field of antibody/protein engineering or flow-based bioassay is recommended.
• Experience in working with mammalian cells, FACS and various cell/molecular techniques (transfection, RNA/protein analysis, immunostaining) are preferred.

Education

• Ph.D. in biochemistry, cell biology, or a related field