Systems Engineer, Bioinstrumentation & MBSE

Exthymic; San Diego (CA); Hybrid; USD 115,000 - 135,000; Full time

Benefits offered by this job

Medical coverage

Dental coverage

Vision coverage

401k match

Job summary

Exthymic is an early-stage deep-tech startup aiming to democratize life-saving cell therapies by integrating hardware, software, and biology. We seek a systems engineer who can manage complex requirements across biology, chemistry, instrumentation, and engineering domains.

You will define interfaces, maintain system architectures, and lead verification planning while coordinating multiple teams. A strong QMS background and hands-on lab experience are essential.

Qualifications

• Bachelor's or Master's degree in an engineering or scientific discipline, or equivalent industry experience.
• 5+ years at the intersection of biology, chemistry, and instrumentation.
• Experience building and maintaining a requirements set in a requirements management tool through research to product development.
• Experience keeping multiple engineering teams aligned across design reviews and interfaces.
• Experience working within a QMS with design history files and supporting artifacts.
• Hands-on laboratory experience and collaboration with bench scientists.

Responsibilities

• Keep one shared picture of what the system must do with requirements tracked in a management tool.
• Define and maintain interfaces between mechanical, electrical, fluidic, software, and cell biology subsystems.
• Maintain interface control documents and system block diagrams; raise integration risks early.
• Support verification and validation planning at subsystem and system level; ensure risks are mitigated in requirements.
• Work with quality and regulatory to keep DHF artifacts current as designs settle.
• Help with prototype assembly and testing with engineering and biology teams; feed learnings back into requirements.

Skills

Systems engineering

Requirements management

Cross‑functional alignment

Interface definition

Verification & validation planning

Risk analysis & mitigation

Prototype assembly & testing

Education

Bachelor's or Master's in engineering or science

Tools

DOORS

Jama

Flow Engineering

Job description

Exthymic is an early-stage deep-tech startup aiming to democratize life-saving cell therapies by integrating hardware, software, and biology. We seek a systems engineer who can manage complex requirements across biology, chemistry, instrumentation, and engineering domains.

You will define interfaces, maintain system architectures, and lead verification planning while coordinating multiple teams. A strong QMS background and hands-on lab experience are essential.