Summer Process Chemistry Co-op: Green & Scalable Routes

Sanofi; Cambridge (MA); On-site; USD 65,000 - 92,000; Part time

Job summary

Sanofi in Cambridge, MA seeks a Summer Co-op in Process Chemistry to join the CMC Synthetics organization. You will design and optimize synthetic routes for drug substances in clinical development, apply green chemistry principles, and collaborate with mentors to deliver scalable manufacturing processes.

You will gain hands-on experience with analytical techniques like NMR and LCMS, and work with tools across photochemistry, flow chemistry, electrochemistry, and AI/ML-based predictive methods

Qualifications

• Currently enrolled in a doctoral degree in Chemistry or a related field.
• Must be permanently authorized to work in the U.S. and not require sponsorship at the time of application or in the future.
• Must be enrolled in an accredited college or university throughout the duration of the co‑op/internship.
• Must be able to relocate to the office location and work 40hrs/week, Monday to Friday for the full duration of the co‑op/internship.
• Preferred Qualifications: Chemistry coursework and lab coursework completed.
• Experience in the use of various analytical instruments (e.g., NMR, LCMS) to interpret analytical data and fully characterize novel organic compounds.

Responsibilities

• Contribute to the design and optimization of novel and efficient synthetic pathways for drug substances undergoing clinical development to demonstrate synthetic viability.
• Use all imaginable chemistry tools and methods to develop and optimize commercial process for selected drug substance route (photochemistry, biocatalysis, flow chemistry, electrochemistry, on-line analysis/PAT, high-throughput experimentation, structural analysis, computational chemistry, AI/ML and predictive tools, etc.).
• Design, plan and execute experimental plans to optimize reaction, purification and isolation unit operations, guided by technical risk assessments, to deliver safe, efficient, robust and scalable drug substance manufacturing processes that perform reliably at intended scale in batch or continuous format.
• Learn to apply green chemistry principles to our R&D programs to develop sustainable manufacturing routes.
• Develop/apply analytical techniques for structural characterization and interpretation (NMR and LCMS).
• Perform data analysis such as interpreting experimental results and designing next steps in collaboration with multiple mentors.
• Maintain electronic laboratory notebooks according to SOP, provide detailed experimental procedures of laboratory work.
• Communicate and interact with other staff/team members in a professional and courteous manner.
• Operate in the lab in a safe and efficient manner according to HSE guidelines and adhere to all mandatory company compliance requirements.

Education

Doctoral degree in Chemistry or related field

Tools

NMR

LCMS

Job description

Sanofi in Cambridge, MA seeks a Summer Co-op in Process Chemistry to join the CMC Synthetics organization. You will design and optimize synthetic routes for drug substances in clinical development, apply green chemistry principles, and collaborate with mentors to deliver scalable manufacturing processes.

You will gain hands-on experience with analytical techniques like NMR and LCMS, and work with tools across photochemistry, flow chemistry, electrochemistry, and AI/ML-based predictive methods