Strategic Leader, Oncology Clinical Development

Tango Therapeutics, Inc; Boston, Northern (MA, KY); Hybrid; USD 250,000 - 450,000; Full time

Job summary

Tango Therapeutics, Inc. is seeking a visionary Executive Director, Clinical Development to lead the clinical development strategy for an early-stage oncology program in Boston.

Reporting to the President of R&D, this role requires partnering with Translational Medicine, BioMetrics, Clinical Pharmacology, Regulatory, Medical Affairs, and senior leadership to align priorities and drive operational excellence.

Qualifications

• Senior medical/oncology leadership experience and strong cross-functional collaboration.
• Expertise in oncology trial design, regulatory strategy, and global regulatory requirements.
• Proven track record building and leading high-performing clinical development teams.

Responsibilities

• Provide strategic leadership for clinical development, including protocol design and regulatory strategy.
• Mentor and develop physicians, fostering scientific excellence and collaboration.
• Oversee preparation of INDs, CTAs, protocols, and briefing packages.
• Partner with project management to drive governance, operational excellence, and program execution.
• Guide trial execution through investigator engagement and patient recruitment strategies.
• Build relationships with key opinion leaders, investigators, and external collaborators.
• Represent Tango at scientific meetings and advisory boards; support scientific communications.

Skills

Leadership

Strategic thinking

Regulatory knowledge

Education

MD with board certification or eligibility in Medical Oncology or Hematology/Oncology

Job description

Tango Therapeutics, Inc. is seeking a visionary Executive Director, Clinical Development to lead the clinical development strategy for an early-stage oncology program in Boston.

Reporting to the President of R&D, this role requires partnering with Translational Medicine, BioMetrics, Clinical Pharmacology, Regulatory, Medical Affairs, and senior leadership to align priorities and drive operational excellence.