Strategic Enterprise Architect – Digital Solutions & Cloud

McKesson; Irving, Northern (TX, KY); Hybrid; USD 187,000 - 312,000; Full time

Job summary

McKesson, a Fortune 10 company, seeks a Principal Enterprise Architect, Digital Solutions to lead enterprise architecture strategy for US Oncology Practices. You’ll align architecture with business goals, partner with executives, and drive secure, scalable digital initiatives across oncology platforms.

You will influence senior leaders, mentor teams, and shape governance as part of a broad, strategic technology agenda that supports patient care and operational excellence.

Qualifications

• 15+ years in enterprise architecture or engineering leadership roles.
• Expertise in cloud modernization, multi-tenant platforms, and large-scale system design.
• Strong integration architecture background with APIs and interoperability standards.
• Experience with data platforms, semantic layers, analytics, and governed access models.
• Familiarity with clinical systems and oncology digital workflows preferred.

Responsibilities

• Define and evolve the enterprise digital architecture vision, principles, and roadmaps aligned with business objectives.
• Provide architectural leadership for major digital initiatives, platform strategies, and transformation programs.
• Advise executives and senior leaders on technology trends, risks, and long-term architectural implications.
• Ensure digital solutions are secure, scalable, interoperable, and compliant with enterprise and regulatory standards.
• Establish and maintain reference architectures, patterns, and governance.
• Influence and mentor architects and technical leaders through thought leadership.

Skills

Enterprise architecture

Cloud modernization

Multi-tenant platforms

System design

APIs & interoperability

Data platforms & analytics

Clinical oncology familiarity

Job description

McKesson, a Fortune 10 company, seeks a Principal Enterprise Architect, Digital Solutions to lead enterprise architecture strategy for US Oncology Practices. You’ll align architecture with business goals, partner with executives, and drive secure, scalable digital initiatives across oncology platforms.

You will influence senior leaders, mentor teams, and shape governance as part of a broad, strategic technology agenda that supports patient care and operational excellence.