Staff Scientist: Membrane Proteins & Cryo-EM Lead

The Scripps Research Institute; San Diego (CA); On-site; USD 78,000 - 109,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Flexible spending accounts

Paid vacation and sick leave

Free on-site parking

Job summary

The Scripps Research Institute in La Jolla, CA, invites applications for a Staff Scientist to lead interdisciplinary projects at the interface of chemical biology and membrane protein science. The role combines cellular assays, protein biochemistry, and structural biology to advance therapeutic targets.

The successful candidate will design and execute experiments, supervise lab members, and collaborate with internal and external partners while developing skills in computational design and

Qualifications

• Ph.D. required with at least 2 years of postdoctoral experience.
• Strong publication or patent record.
• Collaborative and effective communication skills.

Responsibilities

• Design, execute, analyze, interpret and troubleshoot experiments in cell biology, membrane protein biochemistry and structural biology.
• Maintain written reports and present results to research leadership.
• Train and mentor junior lab members.
• Collaborate with internal/external partners and supervise projects.
• Develop robust expression/purification workflows for synthetic and membrane proteins.
• Characterize biophysical properties and interactions of candidate proteins.
• Execute PPI and signaling assays in mammalian cells.

Skills

Protein production

Membrane proteins

Cryo-EM

Mammalian cell culture

Cloning

Biophysics

AI/ML design

Signaling assays

Protein interactions

Western blot / flow cytometry

Education

Ph.D. in related scientific discipline

Tools

None specified

Job description

The Scripps Research Institute in La Jolla, CA, invites applications for a Staff Scientist to lead interdisciplinary projects at the interface of chemical biology and membrane protein science. The role combines cellular assays, protein biochemistry, and structural biology to advance therapeutic targets.

The successful candidate will design and execute experiments, supervise lab members, and collaborate with internal and external partners while developing skills in computational design and