Staff Engineer, Cell Culture Process Development — Data-Driven

Takeda Pharmaceutical Co.; Lexington (MA); On-site; USD 116,000 - 182,000; Full time

Job summary

Takeda Pharmaceutical Co. in Lexington, MA seeks a Staff Engineer, Process Development to advance its cell culture platform through hands-on development and data‑driven approaches. The role blends experimental work with modeling to boost performance, scalability, and robustness of upstream processes.

You will design and execute studies, communicate results, and collaborate with global teams. A PhD or advanced degree with relevant industry experience, plus strong cGMP knowledge, is required.

Qualifications

• PhD in Chemical Engineering, Biochemical Engineering, Bioengineering, Biotechnology, Biological Sciences, or related with relevant industrial experience.
• Master's degree with 6+ years of relevant industry experience.
• Bachelor's degree with 8+ years of relevant industry experience.
• Experience in cell culture process development within a biopharmaceutical CMC environment.
• Strong understanding of cell culture media development, cellular metabolism, and upstream bioprocessing fundamentals.
• Demonstrated interest in data analytics, process modeling, and data-driven process optimization.
• Experience designing, executing, and interpreting laboratory studies using bioreactor systems.
• Excellent scientific communication, problem-solving, and collaboration skills.
• Working knowledge of current Good Manufacturing Practices (cGMP).
• Experience in metabolomics and systems-level process development.
• Experience developing mechanistic, hybrid, or data-driven models for bioprocess development.
• Familiarity with process automation, digital tools, data historians, and advanced analytics platforms.
• Experience supporting clinical development programs and technology transfer activities.

Responsibilities

• Independently design, execute, and interpret cell culture process development experiments.
• Generate and communicate data-driven conclusions and technical recommendations.
• Author study plans, technical reports, presentations, and development documentation.
• Lead and contribute to cross-functional project teams and global initiatives.
• Collaborate with program support teams and modeling experts to deliver project objectives.
• Serve as a technical resource, mentor, and trainer for colleagues.

Skills

Data analytics

Team leadership

Scientific communication

Collaboration

Education

PhD in Chemical/Biochemical/Bioengineering or related

MS with 6+ years of industry experience

BS with 8+ years of industry experience

Tools

Bioreactor systems

Process analytics software

Automation & data historians

Job description

Takeda Pharmaceutical Co. in Lexington, MA seeks a Staff Engineer, Process Development to advance its cell culture platform through hands-on development and data‑driven approaches. The role blends experimental work with modeling to boost performance, scalability, and robustness of upstream processes.

You will design and execute studies, communicate results, and collaborate with global teams. A PhD or advanced degree with relevant industry experience, plus strong cGMP knowledge, is required.