Staff Applied AI Engineer: Scalable AI Backend Lead

Biopharma Careers; St. Louis (MO); On-site; USD 111,000 - 186,000; Full time

Benefits offered by this job

Health insurance

Paid time off (PTO)

Retirement contributions

Other perquisites

Sales or performance-based bonuses (if

Job summary

MilliporeSigma is seeking a Staff Applied AI Engineer to build scalable, production-grade backend applications leveraging large datasets. You’ll work with product managers, software engineers, data scientists, and ML engineers to deliver data-intensive services and AI-powered systems.

The role emphasizes software engineering fundamentals, data lifecycle expertise, and designing scalable, reliable systems for production use. Collaboration across teams is essential to success.

Qualifications

• Bachelor’s degree in Computer Science, Engineering, Data Science, or a related quantitative field.
• At least 3 years of hands-on experience in ML, data science, search relevance, or ranking systems.

Responsibilities

• Lead technical strategy for AI/LLM systems across multiple products.
• Architect retrieval, orchestration, agentic, and evaluation systems that run reliably in production.
• Set the standards for AI safety, evaluation, observability, and responsible rollout in a regulated context.
• Mentor junior engineers into strong AI engineers; employ AI-native development skills to multiply productivity.
• Lead the frontier: evaluate new models, techniques, and tools, and bring the right ones into the team.
• Design, develop, and maintain scalable Python applications and backend services.
• Build systems that ingest, validate, transform, and manage structured and unstructured data in production.
• Design data models and storage solutions for scalable, high-performance apps.
• Develop reusable components for data processing, validation, enrichment, and feature generation.

Skills

Python programming

ML fundamentals

REST API design

Distributed systems

Cloud experience

Education

Bachelor’s degree in Computer Science/Engineering/Data Science

Tools

Docker

Git

CI/CD

Kubernetes

Kafka

Job description

MilliporeSigma is seeking a Staff Applied AI Engineer to build scalable, production-grade backend applications leveraging large datasets. You’ll work with product managers, software engineers, data scientists, and ML engineers to deliver data-intensive services and AI-powered systems.

The role emphasizes software engineering fundamentals, data lifecycle expertise, and designing scalable, reliable systems for production use. Collaboration across teams is essential to success.