Senior AI Backend Engineer for Scalable ML Systems

MilliporeSigma

St. Louis (MO)

On-site

USD 110,500 - 165,900

Full time

14 days+
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Benefits offered by this job

Health insurance
Paid time off (PTO)
Retirement contributions

Job summary

MilliporeSigma is seeking a Staff Applied AI Engineer to build scalable, production-grade backend applications that leverage large datasets and power AI-driven solutions. You will collaborate with product managers, software engineers, data scientists, and ML engineers to deliver robust backend services and data-intensive applications.

Responsibilities include leading AI/LLM strategy, designing reliable data ingestion and processing pipelines, and ensuring safe, observable deployments in

Qualifications

  • Bachelor’s degree in Computer Science, Engineering, Data Science, or a related quantitative field.
  • At least 3 years of hands-on experience in machine learning, data science, search relevance, or ranking systems.

Responsibilities

  • Lead technical strategy for AI/LLM systems across multiple products.
  • Architect retrieval, orchestration, agentic, and evaluation systems that run reliably in production.
  • Set the standards for AI safety, evaluation, observability, and responsible rollout in a regulated context.
  • Mentor Junior engineers into strong AI engineers; employ AI Native development skills to multiply productivity.

Skills

Python
REST API
Pandas
NumPy

Education

Bachelor's degree in CS/Engineering/Data Science

Tools

Docker
Git
CI/CD

Job description

MilliporeSigma is seeking a Staff Applied AI Engineer to build scalable, production-grade backend applications that leverage large datasets and power AI-driven solutions. You will collaborate with product managers, software engineers, data scientists, and ML engineers to deliver robust backend services and data-intensive applications.

Responsibilities include leading AI/LLM strategy, designing reliable data ingestion and processing pipelines, and ensuring safe, observable deployments in

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